Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ADI73586.1PFAM: protein of unknown function DUF112 transmembrane; KEGG: mbu:Mbur_1004 hypothetical protein. (442 aa)    
Predicted Functional Partners:
ADI73585.1
PFAM: PP-loop domain protein; KEGG: mbu:Mbur_0991 hypothetical protein.
       0.658
ADI73790.1
Manually curated; KEGG: mbu:Mbur_1085 hypothetical protein.
  
     0.601
ADI74473.1
PFAM: RNA polymerase Rpb4; KEGG: mba:Mbar_A3232 DNA-directed RNA polymerase, subunit F.
  
     0.594
ADI74114.1
PFAM: conserved hypothetical protein; KEGG: chl:Chy400_3892 hypothetical protein.
     
 0.584
ef1b
Translation elongation factor aEF-1 beta; Promotes the exchange of GDP for GTP in EF-1-alpha/GDP, thus allowing the regeneration of EF-1-alpha/GTP that could then be used to form the ternary complex EF-1-alpha/GTP/AAtRNA.
       0.570
ADI75063.1
KEGG: mbu:Mbur_0155 hypothetical protein.
  
     0.560
ADI74526.1
PFAM: Protein of unknown function DUF2072, Zinc-ribbon; KEGG: mbu:Mbur_0142 hypothetical protein.
  
     0.549
secD
SecD/SecF/SecDF export membrane protein; Involved in protein export.
  
     0.533
rpl12
Ribosomal protein 60S; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the eukaryotic ribosomal protein P1/P2 family.
       0.533
endA
tRNA intron endonuclease; Endonuclease that removes tRNA introns. Cleaves pre-tRNA at the 5' and 3' splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3' cyclic phosphate and 5'-OH termini. Recognizes a pseudosymmetric substrate in which 2 bulged loops of 3 bases are separated by a stem of 4 bp.
 
     0.530
Your Current Organism:
Methanohalobium evestigatum
NCBI taxonomy Id: 644295
Other names: M. evestigatum Z-7303, Methanohalobium evestigatum Z-7303, Methanohalobium evestigatum str. Z-7303, Methanohalobium evestigatum strain Z-7303
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