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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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ADI73645.1KEGG: mba:Mbar_A0218 acetolactate synthase 3 catalytic subunit; TIGRFAM: acetolactate synthase, large subunit, biosynthetic type; PFAM: thiamine pyrophosphate protein TPP binding domain protein; thiamine pyrophosphate protein central region; thiamine pyrophosphate protein domain protein TPP-binding. (561 aa)    
Predicted Functional Partners:
ADI73646.1
TIGRFAM: acetolactate synthase, small subunit; KEGG: mac:MA3791 acetolactate synthase 3 regulatory subunit; PFAM: Acetolactate synthase, small subunit-like; amino acid-binding ACT domain protein.
 
 0.999
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
 
 
 0.999
cimA
Isopropylmalate/citramalate/homocitrate synthase; Catalyzes the condensation of pyruvate and acetyl-coenzyme A to form (R)-citramalate; Belongs to the alpha-IPM synthase/homocitrate synthase family.
  
 
 0.991
ADI73014.1
KEGG: mma:MM_1489 3-isopropylmalate dehydrogenase; PFAM: isocitrate/isopropylmalate dehydrogenase.
  
 0.950
ilvD
TIGRFAM: dihydroxy-acid dehydratase; KEGG: mbu:Mbur_2246 dihydroxy-acid dehydratase; PFAM: dihydroxy-acid and 6-phosphogluconate dehydratase; Belongs to the IlvD/Edd family.
 
 0.945
ADI74481.1
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase; KEGG: mbu:Mbur_0890 pyruvate flavodoxin/ferredoxin oxidoreductase-like protein.
  
 
 0.921
ADI74668.1
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Transketolase domain protein; KEGG: mbu:Mbur_2157 pyruvate ferredoxin oxidoreductase, alpha subunit.
  
 
 0.921
ADI74480.1
TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit; KEGG: mbu:Mbur_0889 2-oxoglutarate ferredoxin oxidoreductase subunit beta; PFAM: thiamine pyrophosphate protein domain protein TPP-binding.
  
 
 0.920
ADI74667.1
PFAM: thiamine pyrophosphate protein domain protein TPP-binding; KEGG: mma:MM_1339 pyruvate synthase beta subunit.
  
 
 0.920
ADI74670.1
KEGG: mbu:Mbur_2155 pyruvate ferredoxin oxidoreductase subunit gamma; TIGRFAM: pyruvate/ketoisovalerate oxidoreductase, gamma subunit; PFAM: Pyruvate/ketoisovalerate oxidoreductase.
  
 
 0.919
Your Current Organism:
Methanohalobium evestigatum
NCBI taxonomy Id: 644295
Other names: M. evestigatum Z-7303, Methanohalobium evestigatum Z-7303, Methanohalobium evestigatum str. Z-7303, Methanohalobium evestigatum strain Z-7303
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