Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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msrBTIGRFAM: methionine-R-sulfoxide reductase; KEGG: mba:Mbar_A0743 methionine sulfoxide reductase B; PFAM: Methionine sulfoxide reductase B; Belongs to the MsrB Met sulfoxide reductase family. (130 aa)    
Predicted Functional Partners:
msrA
Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
 
 0.993
ADI74016.1
PFAM: cytochrome c biogenesis protein transmembrane region; KEGG: mac:MA1389 holocytochrome-c synthase.
  
 0.866
ADI73840.1
TIGRFAM: PAS sensor protein; PFAM: PAS fold-3 domain protein; PAS fold domain protein; GAF domain protein; KEGG: mbu:Mbur_0810 multi-PAS sensor; SMART: PAS domain containing protein; PAC repeat-containing protein; GAF domain protein.
      
 0.812
grpE
GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]
   
 
 0.722
ADI73807.1
KEGG: sfu:Sfum_0406 rhodanese domain-containing protein; PFAM: Rhodanese domain protein; Rubrerythrin; SMART: Rhodanese domain protein.
  
  
 0.698
ADI74550.1
PAS/PAC sensor signal transduction histidine kinase; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; PAS fold-3 domain protein; PAS fold domain protein; KEGG: mac:MA0863 sensory transduction histidine kinase; SMART: ATP-binding region ATPase domain protein; PAS domain containing protein; PAC repeat-containing protein.
     
 0.611
groS
Chaperonin Cpn10; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter.
  
  
 0.531
ADI73612.1
KEGG: mbu:Mbur_0101 thioredoxin reductase; TIGRFAM: thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
  
  
 0.529
rpl11
Ribosomal protein L11-like protein; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors; Belongs to the universal ribosomal protein uL11 family.
   
 
 0.500
cofD
LPPG domain protein containing protein; Catalyzes the transfer of the phosphoenolpyruvate moiety from enoylpyruvoyl-2-diphospho-5'-guanosine (EPPG) to 7,8-didemethyl-8- hydroxy-5-deazariboflavin (FO) with the formation of dehydro coenzyme F420-0 and GMP.
     
 0.485
Your Current Organism:
Methanohalobium evestigatum
NCBI taxonomy Id: 644295
Other names: M. evestigatum Z-7303, Methanohalobium evestigatum Z-7303, Methanohalobium evestigatum str. Z-7303, Methanohalobium evestigatum strain Z-7303
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