Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADI73671.1KEGG: hla:Hlac_1233 membrane protein-like protein. (551 aa)    
Predicted Functional Partners:
ADI74270.1
PFAM: Protein of unknown function DUF555; KEGG: mma:MM_2357 hypothetical protein; Belongs to the UPF0212 family.
 
     0.631
guaAA
GMP synthase, small subunit; Catalyzes the synthesis of GMP from XMP.
 
     0.622
ADI73672.1
Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.
       0.584
ADI72990.1
PFAM: phosphoesterase RecJ domain protein; nucleic acid binding OB-fold tRNA/helicase-type; RNA binding S1 domain protein; KEGG: mma:MM_2034 hypothetical protein.
  
     0.501
ADI73670.1
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: mma:MM_0760 ferredoxin.
       0.494
ADI73638.1
KEGG: mbu:Mbur_0116 ATP-binding protein.
  
     0.479
ADI74734.1
KEGG: mbu:Mbur_0179 DEAD/DEAH box helicase-like protein; PFAM: DEAD/DEAH box helicase domain protein; helicase domain protein; SMART: DEAD-like helicase; helicase domain protein.
  
     0.419
ADI72965.1
PFAM: Protein of unknown function UPF0058; KEGG: mma:MM_1294 hypothetical protein.
 
     0.406
secG
Preprotein translocase subunit SecG; Involved in protein export. The function of the beta subunit is unknown, but it may be involved in stabilization of the trimeric complex.
       0.400
Your Current Organism:
Methanohalobium evestigatum
NCBI taxonomy Id: 644295
Other names: M. evestigatum Z-7303, Methanohalobium evestigatum Z-7303, Methanohalobium evestigatum str. Z-7303, Methanohalobium evestigatum strain Z-7303
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