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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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co-expression
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[Homology]
Score
ADI73698.1KEGG: mba:Mbar_A0623 isocitrate dehydrogenase (NADP); PFAM: isocitrate/isopropylmalate dehydrogenase. (344 aa)    
Predicted Functional Partners:
ADI74312.1
KEGG: mma:MM_1528 aconitate hydratase; TIGRFAM: aconitate hydratase 1; PFAM: aconitate hydratase domain protein.
 
 0.961
ADI74480.1
TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit; KEGG: mbu:Mbur_0889 2-oxoglutarate ferredoxin oxidoreductase subunit beta; PFAM: thiamine pyrophosphate protein domain protein TPP-binding.
  
 
 0.908
ADI74481.1
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase; KEGG: mbu:Mbur_0890 pyruvate flavodoxin/ferredoxin oxidoreductase-like protein.
    
 0.905
ADI75056.1
PFAM: Aldehyde Dehydrogenase; KEGG: mbu:Mbur_0175 succinate-semialdehyde dehydrogenase (NAD(P)+).
   
 0.855
argH
KEGG: mac:MA1318 argininosuccinate lyase; TIGRFAM: argininosuccinate lyase; PFAM: fumarate lyase.
  
 
 0.842
ADI73948.1
PFAM: aminotransferase class I and II; KEGG: mbu:Mbur_0428 aspartate aminotransferase.
  
 0.833
ADI74612.1
PFAM: aminotransferase class I and II; KEGG: mbu:Mbur_1888 aminotransferase.
  
 0.833
ADI73691.1
KEGG: mma:MM_0941 adenylosuccinate lyase; TIGRFAM: adenylosuccinate lyase; PFAM: fumarate lyase; Adenylosuccinate lyase-like; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
  
 
 0.827
leuC
3-isopropylmalate dehydratase; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
 
 
 0.807
hacB
3-isopropylmalate dehydratase, small subunit; Hydro-lyase with broad substrate specificity for cis- unsaturated tricarboxylic acids. Catalyzes both the reversible dehydration of (R)-homocitrate ((R)-2-hydroxybutane-1,2,4- tricarboxylate) to produce cis-homoaconitate ((Z)-but-1-ene-1,2,4- tricarboxylate), and its hydration to homoisocitrate ((1R,2S)-1- hydroxybutane-1,2,4-tricarboxylate). Is also able to hydrate the analogous longer chain substrates cis-homo(2)-aconitate, cis-homo(3)- aconitate. All these reactions are part of the biosynthesis pathway of coenzyme B; Belongs to the LeuD [...]
  
 0.761
Your Current Organism:
Methanohalobium evestigatum
NCBI taxonomy Id: 644295
Other names: M. evestigatum Z-7303, Methanohalobium evestigatum Z-7303, Methanohalobium evestigatum str. Z-7303, Methanohalobium evestigatum strain Z-7303
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