STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADI73798.1Methyl-coenzyme M reductase, alpha subunit; Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2- (methylthio)ethanesulfonate) using coenzyme B (CoB or 7- mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis. (573 aa)    
Predicted Functional Partners:
ADI73799.1
TIGRFAM: methyl-coenzyme M reductase, gamma subunit; KEGG: mba:Mbar_A0894 methyl-coenzyme M reductase, gamma subunit; PFAM: Methyl-coenzyme M reductase, gamma subunit.
 
 0.999
ADI73800.1
KEGG: mbu:Mbur_2419 methyl-coenzyme M reductase operon protein C; TIGRFAM: methyl-coenzyme M reductase I operon protein C; PFAM: Methyl-coenzyme M reductase protein C.
 
 
 0.999
ADI73802.1
TIGRFAM: methyl-coenzyme M reductase, beta subunit; KEGG: mma:MM_1244 methyl-coenzyme M reductase, beta subunit; PFAM: Methyl-coenzyme M reductase, beta subunit.
 
 0.999
ADI73801.1
KEGG: mbu:Mbur_2420 methyl-coenzyme M reductase, protein D; TIGRFAM: methyl-coenzyme M reductase operon protein D; PFAM: Methyl-coenzyme M reductase, protein D.
 
 
 0.998
ADI74649.1
TIGRFAM: methyl coenzyme M reductase system, component A2; PFAM: ABC transporter related; KEGG: mbu:Mbur_1902 ABC transporter, fused ATPase subunits; SMART: AAA ATPase.
 
  
 0.977
ADI74370.1
ABC transporter related protein; KEGG: mac:MA3967 methylcoenzyme M reductase system, component A2; PFAM: ABC transporter related; SMART: AAA ATPase.
 
  
 0.963
mtrA
Tetrahydromethanopterin S-methyltransferase, subunit A; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step; Belongs to the MtrA family.
 
 
 0.909
ADI73804.1
Methanogenesis marker protein 10; KEGG: mbu:Mbur_2422 hypothetical protein; TIGRFAM: methanogenesis marker protein 10; PFAM: protein of unknown function DUF512; Radical SAM domain protein.
 
 
 
 0.905
mtrG
Tetrahydromethanopterin S-methyltransferase, subunit G; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step.
 
 
 0.892
mtrB
Tetrahydromethanopterin S-methyltransferase subunit B; Part of a complex that catalyzes the formation of methyl- coenzyme M and tetrahydromethanopterin from coenzyme M and methyl- tetrahydromethanopterin. This is an energy-conserving, sodium-ion translocating step.
 
 
 0.877
Your Current Organism:
Methanohalobium evestigatum
NCBI taxonomy Id: 644295
Other names: M. evestigatum Z-7303, Methanohalobium evestigatum Z-7303, Methanohalobium evestigatum str. Z-7303, Methanohalobium evestigatum strain Z-7303
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