Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADI73806.1PFAM: Methyltransferase type 11; KEGG: mbu:Mbur_0084 methyltransferase type 11. (209 aa)    
Predicted Functional Partners:
ADI75050.1
PFAM: Methyltransferase type 11; KEGG: sit:TM1040_1749 methyltransferase type 12.
  
     0.596
polC
DNA polymerase II, large subunit DP2; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase.
       0.590
rps5
Ribosomal protein S5; With S4 and S12 plays an important role in translational accuracy.
    
 0.578
ADI73200.1
TIGRFAM: NADH-quinone oxidoreductase, B subunit; KEGG: mac:MA1496 F(420)H(2) dehydrogenase, subunit FpoB; PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; Belongs to the complex I 20 kDa subunit family.
   
 0.517
rps9
KEGG: mbu:Mbur_2390 30S ribosomal protein S9P; TIGRFAM: ribosomal protein S9P; PFAM: ribosomal protein S9; Belongs to the universal ribosomal protein uS9 family.
  
 
 0.514
ADI73202.1
NADH dehydrogenase (quinone); KEGG: mac:MA1498 F(420)H(2) dehydrogenase, subunit FpoD; PFAM: NADH-ubiquinone oxidoreductase chain 49kDa.
   
 0.465
Your Current Organism:
Methanohalobium evestigatum
NCBI taxonomy Id: 644295
Other names: M. evestigatum Z-7303, Methanohalobium evestigatum Z-7303, Methanohalobium evestigatum str. Z-7303, Methanohalobium evestigatum strain Z-7303
Server load: low (12%) [HD]