Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ADI73829.1PFAM: 6-phosphogluconate dehydrogenase NAD-binding; KEGG: mbu:Mbur_2083 hypothetical protein. (260 aa)    
Predicted Functional Partners:
ADI73830.1
PFAM: protein of unknown function DUF201; KEGG: mma:MM_1443 hypothetical protein.
 
  
 0.999
ADI73831.1
Radical SAM domain protein; KEGG: mbu:Mbur_2085 biotin synthase; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB.
 
   
 0.991
pylS
pyrrolysyl-tRNA synthetase; Catalyzes the attachment of pyrrolysine to tRNA(Pyl). Pyrrolysine is a lysine derivative encoded by the termination codon UAG.
 
   
 0.987
ADI73954.1
KEGG: mac:MA0144 monomethylamine methyltransferase; manually curated; PFAM: Monomethylamine methyltransferase MtmB.
 
   
 0.718
ADI74208.1
KEGG: mac:MA0144 monomethylamine methyltransferase; manually curated; PFAM: Monomethylamine methyltransferase MtmB.
 
   
 0.718
ADI74779.1
PFAM: protein of unknown function DUF6 transmembrane; KEGG: mma:MM_2046 trimethylamine permease.
  
     0.686
ADI74781.1
Trimethylamine; Manually curated; TIGRFAM: trimethylamine; KEGG: mac:MA0932 trimethylamine methyltransferase; PFAM: trimethylamine methyltransferase.
  
     0.674
ADI74491.1
PFAM: Protein of unknown function DUF1638; KEGG: mma:MM_0584 hypothetical protein.
 
     0.634
ADI73838.1
KEGG: mac:MA1616 methanol-5-hydroxybenzimidazolylcobamide co-methyltransferase, isozyme 3.
  
     0.632
ADI74320.1
PFAM: Monomethylamine methyltransferase MtmB; KEGG: mac:MA0144 monomethylamine methyltransferase.
 
   
 0.616
Your Current Organism:
Methanohalobium evestigatum
NCBI taxonomy Id: 644295
Other names: M. evestigatum Z-7303, Methanohalobium evestigatum Z-7303, Methanohalobium evestigatum str. Z-7303, Methanohalobium evestigatum strain Z-7303
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