Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADI73831.1Radical SAM domain protein; KEGG: mbu:Mbur_2085 biotin synthase; PFAM: Radical SAM domain protein; SMART: Elongator protein 3/MiaB/NifB. (346 aa)    
Predicted Functional Partners:
ADI73830.1
PFAM: protein of unknown function DUF201; KEGG: mma:MM_1443 hypothetical protein.
 
 
 0.999
ADI73829.1
PFAM: 6-phosphogluconate dehydrogenase NAD-binding; KEGG: mbu:Mbur_2083 hypothetical protein.
 
   
 0.991
pylS
pyrrolysyl-tRNA synthetase; Catalyzes the attachment of pyrrolysine to tRNA(Pyl). Pyrrolysine is a lysine derivative encoded by the termination codon UAG.
 
   
 0.966
lysA
Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
    
 0.925
ADI73649.1
PFAM: DNA topoisomerase type IA central domain protein; TOPRIM domain protein; DNA topoisomerase type IA zn finger domain protein; KEGG: mbu:Mbur_0705 DNA topoisomerase; SMART: DNA topoisomerase I DNA-binding; DNA topoisomerase I ATP-binding; Toprim sub domain protein.
 
   
 0.823
ADI74198.1
PFAM: sodium/hydrogen exchanger; TrkA-N domain protein; TrkA-C domain protein; KEGG: mbu:Mbur_1461 sodium/hydrogen exchanger.
 
    0.809
ADI74705.1
KEGG: mpl:Mpal_1151 PP-loop domain-containing protein.
  
    0.807
ADI73212.1
PFAM: nucleoside recognition domain protein; KEGG: mac:MA3285 hypothetical protein.
  
    0.677
ADI74091.1
PFAM: Abortive infection protein; KEGG: xce:Xcel_2718 abortive infection protein.
  
    0.655
ADI73440.1
TIGRFAM: biotin/acetyl-CoA-carboxylase ligase; KEGG: mba:Mbar_A1588 biotin--(acetyl-CoA-carboxylase) synthetase; PFAM: biotin/lipoate A/B protein ligase; Helix-turn-helix type 11 domain protein; biotin protein ligase domain protein.
  
  
 0.639
Your Current Organism:
Methanohalobium evestigatum
NCBI taxonomy Id: 644295
Other names: M. evestigatum Z-7303, Methanohalobium evestigatum Z-7303, Methanohalobium evestigatum str. Z-7303, Methanohalobium evestigatum strain Z-7303
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