Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADI73877.1PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: mac:MA0255 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate synthesis protein ThiF. (241 aa)    
Predicted Functional Partners:
ADI73413.1
MoaD family protein; KEGG: mma:MM_0831 molybdopterin converting factor small subunit; TIGRFAM: MoaD family protein; PFAM: thiamineS protein.
 
 0.994
iscS
Cysteine desulfurase NifS; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins.
   
 0.990
rpl40e
KEGG: mac:MA3970 50S ribosomal protein L40e; Belongs to the eukaryotic ribosomal protein eL40 family.
   
 0.948
ADI74499.1
KEGG: mbu:Mbur_0381 molybdopterin-guanine dinucleotide biosynthesis protein B; TIGRFAM: molybdopterin-guanine dinucleotide biosynthesis protein B; PFAM: molybdopterin biosynthesis MoaE protein; molybdopterin-guanine dinucleotide biosynthesis MobB region.
 
 0.932
ADI74715.1
KEGG: mac:MA4350 molybdenum cofactor biosynthesis protein; TIGRFAM: molybdenum cofactor synthesis domain protein; PFAM: MoeA domain protein domain I and II; molybdopterin binding domain; MoeA domain protein domain IV.
 
  
 0.924
ADI73807.1
KEGG: sfu:Sfum_0406 rhodanese domain-containing protein; PFAM: Rhodanese domain protein; Rubrerythrin; SMART: Rhodanese domain protein.
    
 0.922
ADI74603.1
Putative transcriptional regulator, ModE family; PFAM: TOBE domain protein; regulatory protein LysR; KEGG: mac:MA0283 molybdenum-binding protein.
 
   
 0.879
ADI73941.1
KEGG: mbu:Mbur_0377 hypothetical protein.
  
 
 0.878
ADI73113.1
KEGG: mbu:Mbur_2182 phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1; Phosphomethylpyrimidine kinase.
 
  
 0.787
alaS
alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
  
 0.753
Your Current Organism:
Methanohalobium evestigatum
NCBI taxonomy Id: 644295
Other names: M. evestigatum Z-7303, Methanohalobium evestigatum Z-7303, Methanohalobium evestigatum str. Z-7303, Methanohalobium evestigatum strain Z-7303
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