Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADI73879.1Redox-active disulfide protein 2; Does not function as a glutathione-disulfide oxidoreductase in the presence of glutathione and glutathione reductase. Has low thioredoxin activity in vitro. (79 aa)    
Predicted Functional Partners:
ADI73065.1
PFAM: permease; KEGG: mac:MA3941 hypothetical protein.
 
  
 0.814
msrA
Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
   
 0.666
ADI73878.1
PFAM: peptidase S1 and S6 chymotrypsin/Hap; KEGG: nmr:Nmar_1146 2-alkenal reductase; SMART: PDZ/DHR/GLGF domain protein.
  
 
 0.614
dnaK
Chaperone protein DnaK; Acts as a chaperone.
  
 0.611
ADI74013.1
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
  
 0.599
ADI74232.1
Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.
  
 0.599
ADI73612.1
KEGG: mbu:Mbur_0101 thioredoxin reductase; TIGRFAM: thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
  
 
 0.568
ADI73064.1
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: mma:MM_3279 dihydrolipoamide dehydrogenase; Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
  
 0.562
ADI73656.1
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: mac:MA4013 glutathione reductase (NADPH).
  
 0.562
ADI74694.1
PFAM: permease; KEGG: mbu:Mbur_1966 hypothetical protein.
 
  
 0.519
Your Current Organism:
Methanohalobium evestigatum
NCBI taxonomy Id: 644295
Other names: M. evestigatum Z-7303, Methanohalobium evestigatum Z-7303, Methanohalobium evestigatum str. Z-7303, Methanohalobium evestigatum strain Z-7303
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