Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
mptDProtein of unknown function DUF381; Catalyzes the conversion of 7,8-dihydroneopterin (H2Neo) to 6-hydroxymethyl-7,8-dihydropterin (6-HMD); Belongs to the archaeal dihydroneopterin aldolase family. (124 aa)    
Predicted Functional Partners:
mptE
Protein of unknown function DUF115; Catalyzes the transfer of diphosphate from ATP to 6- hydroxymethyl-7,8-dihydropterin (6-HMD), leading to 6-hydroxymethyl- 7,8-dihydropterin diphosphate (6-HMDP); Belongs to the archaeal 6-HMPDK family.
 
  
 0.977
ADI73000.1
TIGRFAM: dihydropteroate synthase; KEGG: mbu:Mbur_1815 dihydropteroate synthase; PFAM: dihydropteroate synthase DHPS.
    
 0.922
ADI74001.1
KEGG: mbu:Mbur_2198 archaetidylserine synthase; TIGRFAM: CDP-diacylglycerol/serine O-phosphatidyltransferase; PFAM: CDP-alcohol phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
       0.914
asd
Phosphatidylserine decarboxylase related protein; Catalyzes the formation of archaetidylethanolamine (PtdEtn) from archaetidylserine (PtdSer); Belongs to the phosphatidylserine decarboxylase family. PSD-A subfamily.
       0.912
ADI74003.1
PFAM: Exosortase EpsH-related; KEGG: mbu:Mbur_2196 hypothetical protein.
       0.912
ADI73697.1
PFAM: TatD-related deoxyribonuclease; KEGG: mbu:Mbur_1153 TatD-related deoxyribonuclease.
 
     0.676
ADI73472.1
PFAM: Protein of unknown function UPF0179; KEGG: mba:Mbar_A0292 hypothetical protein; Belongs to the UPF0179 family.
  
     0.659
ADI74404.1
JAMM-like protein; Metallo peptidase. MEROPS family M67B; KEGG: mbu:Mbur_0623 JAMM-like protein. Metallo peptidase. MEROPS family M67B.
  
     0.641
mptA
Protein of unknown function DUF198; Converts GTP to 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate, the first intermediate in the biosynthesis of coenzyme methanopterin.
 
   
 0.626
ADI72996.1
Transcriptional regulator, XRE family; KEGG: mbu:Mbur_1811 hypothetical protein; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein.
  
     0.611
Your Current Organism:
Methanohalobium evestigatum
NCBI taxonomy Id: 644295
Other names: M. evestigatum Z-7303, Methanohalobium evestigatum Z-7303, Methanohalobium evestigatum str. Z-7303, Methanohalobium evestigatum strain Z-7303
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.