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cbiA-2Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the ATP- dependent amidation of the two carboxylate groups at positions a and c of Ni-sirohydrochlorin, using L-glutamine or ammonia as the nitrogen source. (440 aa)    
Predicted Functional Partners:
ADI73038.1
PFAM: Precorrin-8X methylmutase CbiC/CobH; KEGG: mbu:Mbur_2355 precorrin-8X methylmutase.
 
 0.992
ADI74133.1
Magnesium chelatase; KEGG: mac:MA0346 protoporphyrin IX magnesium chelatase; PFAM: CobN/magnesium chelatase.
 
 
 0.954
cobQ
Cobyric acid synthase CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
  
 0.904
ADI73037.1
TIGRFAM: precorrin-3B C17-methyltransferase; KEGG: mbu:Mbur_2356 precorrin-3 methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase.
 
  
 0.896
ADI73035.1
PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; KEGG: mbu:Mbur_2359 cobalt-precorrin-2 C(20)-methyltransferase; Belongs to the precorrin methyltransferase family.
 
  
 0.838
cobD
Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
  
 0.830
moaA
Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate; Belongs to the radical SAM superfamily. MoaA family.
       0.824
cbiT
precorrin-6Y C5,15-methyltransferase (decarboxylating), CbiT subunit; Catalyzes the methylation of C-15 in cobalt-precorrin-6B followed by the decarboxylation of C-12 to form cobalt-precorrin-7.
 
  
 0.801
cbiD
Cobalamin (vitamin B12) biosynthesis CbiD protein; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
 
  
 0.801
ADI73890.1
PFAM: aminotransferase class I and II; cysteine-rich small domain; KEGG: mba:Mbar_A3453 L-threonine O-3-phosphate decarboxylase.
  
 0.797
Your Current Organism:
Methanohalobium evestigatum
NCBI taxonomy Id: 644295
Other names: M. evestigatum Z-7303, Methanohalobium evestigatum Z-7303, Methanohalobium evestigatum str. Z-7303, Methanohalobium evestigatum strain Z-7303
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