STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADI74150.1PFAM: Uroporphyrinogen decarboxylase (URO-D); KEGG: mac:MA0847 methyltransferase. (358 aa)    
Predicted Functional Partners:
ADI73231.1
PFAM: Uroporphyrinogen III synthase HEM4; KEGG: mac:MA3034 uroporphyrinogen-III synthase.
  
 
 0.915
ADI74962.1
Uroporphyrinogen III synthase HEM4; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
  
 
 0.915
ADI73230.1
KEGG: mma:MM_0307 uroporphyrin-III C-methyltransferase; TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Belongs to the precorrin methyltransferase family.
    
 0.913
ADI73694.1
PFAM: Uroporphyrinogen decarboxylase (URO-D); KEGG: mac:MA0847 methyltransferase.
  
  
 
0.900
ADI72944.1
Methyltransferase MtaA/CmuA family; KEGG: mac:MA2163 methylcobalamin:coenzyme M methyltransferase; TIGRFAM: methyltransferase MtaA/CmuA family; PFAM: Uroporphyrinogen decarboxylase (URO-D).
 
   
 0.747
ADI73842.1
KEGG: mma:MM_0940 putative flavoprotein.
 
   
 0.678
ADI74783.1
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: mbu:Mbur_1370 4Fe-4S ferredoxin, iron-sulfur binding.
 
   
 0.661
ADI74545.1
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: mbu:Mbur_1370 4Fe-4S ferredoxin, iron-sulfur binding.
 
   
 0.659
ADI74491.1
PFAM: Protein of unknown function DUF1638; KEGG: mma:MM_0584 hypothetical protein.
  
     0.556
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps.
  
 
 0.532
Your Current Organism:
Methanohalobium evestigatum
NCBI taxonomy Id: 644295
Other names: M. evestigatum Z-7303, Methanohalobium evestigatum Z-7303, Methanohalobium evestigatum str. Z-7303, Methanohalobium evestigatum strain Z-7303
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.