STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADI74325.1TIGRFAM: CoB/CoM heterodisulfide reductase, subunit B; KEGG: mma:MM_0980 heterodisulfide reductase subunit HdrB; PFAM: protein of unknown function DUF224 cysteine-rich region domain protein. (301 aa)    
Predicted Functional Partners:
ADI74295.1
Methyl-viologen-reducing hydrogenase delta subunit; Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B).
 
 0.999
ADI74326.1
KEGG: mac:MA4236 heterodisulfide reductase, subunit C; TIGRFAM: CoB/CoM heterodisulfide reductase, subunit C.
 
 0.999
ADI74384.1
PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; KEGG: mbu:Mbur_0470 hypothetical protein.
 
 0.951
ADI73453.1
KEGG: mac:MA0688 heterodisulfide reductase, subunit D; PFAM: protein of unknown function DUF224 cysteine-rich region domain protein.
 
0.947
ADI73452.1
KEGG: mbu:Mbur_2436 CoB-CoM heterodisulfide reductase, subunit E.
     
 0.922
ADI73798.1
Methyl-coenzyme M reductase, alpha subunit; Component of the methyl-coenzyme M reductase (MCR) I that catalyzes the reductive cleavage of methyl-coenzyme M (CoM-S-CH3 or 2- (methylthio)ethanesulfonate) using coenzyme B (CoB or 7- mercaptoheptanoylthreonine phosphate) as reductant which results in the production of methane and the mixed heterodisulfide of CoB and CoM (CoM-S-S-CoB). This is the final step in methanogenesis.
 
  
 0.791
ADI73802.1
TIGRFAM: methyl-coenzyme M reductase, beta subunit; KEGG: mma:MM_1244 methyl-coenzyme M reductase, beta subunit; PFAM: Methyl-coenzyme M reductase, beta subunit.
 
  
 0.763
ADI74296.1
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: mbu:Mbur_0553 formylmethanofuran dehydrogenase, subunit F.
 
 
 
 0.762
ADI74287.1
PFAM: molydopterin dinucleotide-binding region; KEGG: mba:Mbar_A2923 formylmethanofuran dehydrogenase, subunit D.
 
 
 
 0.758
ADI74585.1
PFAM: molydopterin dinucleotide-binding region; KEGG: mac:MA0835 formylmethanofuran dehydrogenase, subunit D.
 
 
 
 0.756
Your Current Organism:
Methanohalobium evestigatum
NCBI taxonomy Id: 644295
Other names: M. evestigatum Z-7303, Methanohalobium evestigatum Z-7303, Methanohalobium evestigatum str. Z-7303, Methanohalobium evestigatum strain Z-7303
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.