Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADI74445.1PFAM: Di-trans-poly-cis-decaprenylcistransferase; KEGG: cac:CAC1432 undecaprenyl pyrophosphate synthase related enzyme. (219 aa)    
Predicted Functional Partners:
ADI74683.1
PFAM: Di-trans-poly-cis-decaprenylcistransferase; KEGG: mma:MM_1083 undecaprenyl pyrophosphate synthetase.
  
  
  0.956
ADI73649.1
PFAM: DNA topoisomerase type IA central domain protein; TOPRIM domain protein; DNA topoisomerase type IA zn finger domain protein; KEGG: mbu:Mbur_0705 DNA topoisomerase; SMART: DNA topoisomerase I DNA-binding; DNA topoisomerase I ATP-binding; Toprim sub domain protein.
  
  
 0.706
valS
valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 2 subfamily.
  
  
 0.633
pyrH
Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP.
 
  
 0.586
ADI74508.1
Peptidase M50; KEGG: mbu:Mbur_0248 peptidase M50; PFAM: peptidase M50; PDZ/DHR/GLGF domain protein; SMART: PDZ/DHR/GLGF domain protein.
  
  
 0.545
nusA
NusA family KH domain protein; Participates in transcription termination. Belongs to the NusA family.
  
    0.523
ADI73160.1
PFAM: Polyprenyl synthetase; KEGG: mbu:Mbur_1235 polyprenyl synthetase; Belongs to the FPP/GGPP synthase family.
 
  
 0.498
ADI74444.1
KEGG: mba:Mbar_A0728 hypothetical protein.
       0.497
pyrG
CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
  
  
 0.486
ADI73683.1
PFAM: RNA polymerase beta subunit; RNA polymerase Rpb2 domain 2; RNA polymerase Rpb2 domain 3; KEGG: mbu:Mbur_1179 DNA-directed RNA polymerase subunit beta''; Belongs to the RNA polymerase beta chain family.
  
  
 0.465
Your Current Organism:
Methanohalobium evestigatum
NCBI taxonomy Id: 644295
Other names: M. evestigatum Z-7303, Methanohalobium evestigatum Z-7303, Methanohalobium evestigatum str. Z-7303, Methanohalobium evestigatum strain Z-7303
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