| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADI73479.1 | ADI73649.1 | Metev_0568 | Metev_0748 | TIGRFAM: DNA-directed RNA polymerase; KEGG: mbu:Mbur_2280 DNA-directed RNA polymerase subunit E'; PFAM: RNA polymerase Rpb7 domain protein; RNA binding S1 domain protein. | PFAM: DNA topoisomerase type IA central domain protein; TOPRIM domain protein; DNA topoisomerase type IA zn finger domain protein; KEGG: mbu:Mbur_0705 DNA topoisomerase; SMART: DNA topoisomerase I DNA-binding; DNA topoisomerase I ATP-binding; Toprim sub domain protein. | 0.719 |
| ADI73479.1 | ADI74503.1 | Metev_0568 | Metev_1663 | TIGRFAM: DNA-directed RNA polymerase; KEGG: mbu:Mbur_2280 DNA-directed RNA polymerase subunit E'; PFAM: RNA polymerase Rpb7 domain protein; RNA binding S1 domain protein. | PFAM: RIO-like kinase; KEGG: mbu:Mbur_1195 O-sialoglycoprotein endopeptidase. | 0.627 |
| ADI73479.1 | ADI74504.1 | Metev_0568 | Metev_1664 | TIGRFAM: DNA-directed RNA polymerase; KEGG: mbu:Mbur_2280 DNA-directed RNA polymerase subunit E'; PFAM: RNA polymerase Rpb7 domain protein; RNA binding S1 domain protein. | Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.616 |
| ADI73479.1 | eif2g | Metev_0568 | Metev_0566 | TIGRFAM: DNA-directed RNA polymerase; KEGG: mbu:Mbur_2280 DNA-directed RNA polymerase subunit E'; PFAM: RNA polymerase Rpb7 domain protein; RNA binding S1 domain protein. | Protein synthesis factor GTP-binding protein; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily. | 0.883 |
| ADI73479.1 | infB | Metev_0568 | Metev_1402 | TIGRFAM: DNA-directed RNA polymerase; KEGG: mbu:Mbur_2280 DNA-directed RNA polymerase subunit E'; PFAM: RNA polymerase Rpb7 domain protein; RNA binding S1 domain protein. | Translation initiation factor aIF-2; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2. | 0.529 |
| ADI73479.1 | kae1 | Metev_0568 | Metev_1662 | TIGRFAM: DNA-directed RNA polymerase; KEGG: mbu:Mbur_2280 DNA-directed RNA polymerase subunit E'; PFAM: RNA polymerase Rpb7 domain protein; RNA binding S1 domain protein. | Metalloendopeptidase, glycoprotease family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Kae1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. | 0.654 |
| ADI73479.1 | rps15 | Metev_0568 | Metev_0205 | TIGRFAM: DNA-directed RNA polymerase; KEGG: mbu:Mbur_2280 DNA-directed RNA polymerase subunit E'; PFAM: RNA polymerase Rpb7 domain protein; RNA binding S1 domain protein. | PFAM: Ribosomal S13S15 domain protein; ribosomal protein S15; KEGG: mbu:Mbur_2345 30S ribosomal protein S15P. | 0.470 |
| ADI73479.1 | rps24e | Metev_0568 | Metev_0571 | TIGRFAM: DNA-directed RNA polymerase; KEGG: mbu:Mbur_2280 DNA-directed RNA polymerase subunit E'; PFAM: RNA polymerase Rpb7 domain protein; RNA binding S1 domain protein. | PFAM: Ribosomal protein S24e; KEGG: mma:MM_0599 30S ribosomal protein S24e; Belongs to the eukaryotic ribosomal protein eS24 family. | 0.946 |
| ADI73649.1 | ADI73479.1 | Metev_0748 | Metev_0568 | PFAM: DNA topoisomerase type IA central domain protein; TOPRIM domain protein; DNA topoisomerase type IA zn finger domain protein; KEGG: mbu:Mbur_0705 DNA topoisomerase; SMART: DNA topoisomerase I DNA-binding; DNA topoisomerase I ATP-binding; Toprim sub domain protein. | TIGRFAM: DNA-directed RNA polymerase; KEGG: mbu:Mbur_2280 DNA-directed RNA polymerase subunit E'; PFAM: RNA polymerase Rpb7 domain protein; RNA binding S1 domain protein. | 0.719 |
| ADI73649.1 | ADI74503.1 | Metev_0748 | Metev_1663 | PFAM: DNA topoisomerase type IA central domain protein; TOPRIM domain protein; DNA topoisomerase type IA zn finger domain protein; KEGG: mbu:Mbur_0705 DNA topoisomerase; SMART: DNA topoisomerase I DNA-binding; DNA topoisomerase I ATP-binding; Toprim sub domain protein. | PFAM: RIO-like kinase; KEGG: mbu:Mbur_1195 O-sialoglycoprotein endopeptidase. | 0.849 |
| ADI73649.1 | ADI74504.1 | Metev_0748 | Metev_1664 | PFAM: DNA topoisomerase type IA central domain protein; TOPRIM domain protein; DNA topoisomerase type IA zn finger domain protein; KEGG: mbu:Mbur_0705 DNA topoisomerase; SMART: DNA topoisomerase I DNA-binding; DNA topoisomerase I ATP-binding; Toprim sub domain protein. | Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.789 |
| ADI73649.1 | eif2g | Metev_0748 | Metev_0566 | PFAM: DNA topoisomerase type IA central domain protein; TOPRIM domain protein; DNA topoisomerase type IA zn finger domain protein; KEGG: mbu:Mbur_0705 DNA topoisomerase; SMART: DNA topoisomerase I DNA-binding; DNA topoisomerase I ATP-binding; Toprim sub domain protein. | Protein synthesis factor GTP-binding protein; eIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EIF2G subfamily. | 0.550 |
| ADI73649.1 | fusA | Metev_0748 | Metev_0775 | PFAM: DNA topoisomerase type IA central domain protein; TOPRIM domain protein; DNA topoisomerase type IA zn finger domain protein; KEGG: mbu:Mbur_0705 DNA topoisomerase; SMART: DNA topoisomerase I DNA-binding; DNA topoisomerase I ATP-binding; Toprim sub domain protein. | Translation elongation factor aEF-2; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF [...] | 0.897 |
| ADI73649.1 | infB | Metev_0748 | Metev_1402 | PFAM: DNA topoisomerase type IA central domain protein; TOPRIM domain protein; DNA topoisomerase type IA zn finger domain protein; KEGG: mbu:Mbur_0705 DNA topoisomerase; SMART: DNA topoisomerase I DNA-binding; DNA topoisomerase I ATP-binding; Toprim sub domain protein. | Translation initiation factor aIF-2; Function in general translation initiation by promoting the binding of the formylmethionine-tRNA to ribosomes. Seems to function along with eIF-2. | 0.881 |
| ADI73649.1 | kae1 | Metev_0748 | Metev_1662 | PFAM: DNA topoisomerase type IA central domain protein; TOPRIM domain protein; DNA topoisomerase type IA zn finger domain protein; KEGG: mbu:Mbur_0705 DNA topoisomerase; SMART: DNA topoisomerase I DNA-binding; DNA topoisomerase I ATP-binding; Toprim sub domain protein. | Metalloendopeptidase, glycoprotease family; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is a component of the KEOPS complex that is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Kae1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. | 0.861 |
| ADI73649.1 | rps15 | Metev_0748 | Metev_0205 | PFAM: DNA topoisomerase type IA central domain protein; TOPRIM domain protein; DNA topoisomerase type IA zn finger domain protein; KEGG: mbu:Mbur_0705 DNA topoisomerase; SMART: DNA topoisomerase I DNA-binding; DNA topoisomerase I ATP-binding; Toprim sub domain protein. | PFAM: Ribosomal S13S15 domain protein; ribosomal protein S15; KEGG: mbu:Mbur_2345 30S ribosomal protein S15P. | 0.905 |
| ADI74503.1 | ADI73479.1 | Metev_1663 | Metev_0568 | PFAM: RIO-like kinase; KEGG: mbu:Mbur_1195 O-sialoglycoprotein endopeptidase. | TIGRFAM: DNA-directed RNA polymerase; KEGG: mbu:Mbur_2280 DNA-directed RNA polymerase subunit E'; PFAM: RNA polymerase Rpb7 domain protein; RNA binding S1 domain protein. | 0.627 |
| ADI74503.1 | ADI73649.1 | Metev_1663 | Metev_0748 | PFAM: RIO-like kinase; KEGG: mbu:Mbur_1195 O-sialoglycoprotein endopeptidase. | PFAM: DNA topoisomerase type IA central domain protein; TOPRIM domain protein; DNA topoisomerase type IA zn finger domain protein; KEGG: mbu:Mbur_0705 DNA topoisomerase; SMART: DNA topoisomerase I DNA-binding; DNA topoisomerase I ATP-binding; Toprim sub domain protein. | 0.849 |
| ADI74503.1 | ADI74504.1 | Metev_1663 | Metev_1664 | PFAM: RIO-like kinase; KEGG: mbu:Mbur_1195 O-sialoglycoprotein endopeptidase. | Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.943 |
| ADI74503.1 | ADI74761.1 | Metev_1663 | Metev_1931 | PFAM: RIO-like kinase; KEGG: mbu:Mbur_1195 O-sialoglycoprotein endopeptidase. | PFAM: Protein of unknown function DUF509; KEGG: mbu:Mbur_1355 hypothetical protein. | 0.865 |