STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADI74646.1KEGG: cpf:CPF_0326 methylated-DNA-[protein]-cysteine S-methyltransferase; TIGRFAM: methylated-DNA/protein-cysteine methyltransferase; PFAM: Methylated-DNA-[protein]-cysteine S-methyltransferase DNA binding. (126 aa)    
Predicted Functional Partners:
ADI74647.1
KEGG: mba:Mbar_A0699 hypothetical protein; PFAM: peptidase M10A and M12B matrixin and adamalysin; SMART: peptidase metallopeptidase.
 
     0.824
truA
tRNA pseudouridine synthase A; Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs; Belongs to the tRNA pseudouridine synthase TruA family.
  
  
 0.511
ADI73370.1
Deoxyribonuclease I; PFAM: Endonuclease/exonuclease/phosphatase; KEGG: mba:Mbar_A2969 hypothetical protein; SMART: deoxyribonuclease I.
 
   
 0.505
uvrC
Excinuclease ABC, C subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.
     
 0.476
uvrB
Excinuclease ABC, B subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
     
 0.461
dbh
DNA-directed DNA polymerase; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis.
 
   
 0.461
ADI73878.1
PFAM: peptidase S1 and S6 chymotrypsin/Hap; KEGG: nmr:Nmar_1146 2-alkenal reductase; SMART: PDZ/DHR/GLGF domain protein.
 
   0.454
ADI73355.1
PFAM: amino acid permease-associated region; UspA domain protein; KEGG: mma:MM_0530 amino acid permease.
  
  
 0.447
ADI75035.1
DEAD_2 domain protein; KEGG: mbu:Mbur_1566 Rad3-related DNA helicases; PFAM: DEAD_2 domain protein; SMART: helicase c2; Helicase-like, DEXD box c2 type; DEAD-like helicase.
     
 0.415
ADI73080.1
PFAM: SMC domain protein; KEGG: sto:ST2117 hypothetical protein.
 
 
 
 0.410
Your Current Organism:
Methanohalobium evestigatum
NCBI taxonomy Id: 644295
Other names: M. evestigatum Z-7303, Methanohalobium evestigatum Z-7303, Methanohalobium evestigatum str. Z-7303, Methanohalobium evestigatum strain Z-7303
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