Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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pelATranslation factor pelota; May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity. (348 aa)    
Predicted Functional Partners:
ADI74806.1
PFAM: Fibronectin-binding A domain protein; protein of unknown function DUF814; KEGG: mbu:Mbur_1391 hypothetical protein.
 
 
 
 0.938
tuf
Translation elongation factor EF-1, subunit alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.
   
 
 0.811
priS
DNA primase, small subunit; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. [...]
 
     0.791
rpl29
KEGG: mbu:Mbur_0008 50S ribosomal protein L29; TIGRFAM: ribosomal protein L29; PFAM: ribosomal protein L29; Belongs to the universal ribosomal protein uL29 family.
 
 
 
 0.784
ADI73008.1
KEGG: mbu:Mbur_1854 putative ATPase RIL; PFAM: ABC transporter related; metal-binding domain in RNase L inhibitor, RLI; 4Fe-4S ferredoxin iron-sulfur binding domain protein; SMART: AAA ATPase.
 
 
 0.753
ADI74808.1
PFAM: Protein of unknown function DUF1288; KEGG: mbu:Mbur_1393 hypothetical protein.
 
     0.731
eif5a
Translation initiation factor eIF-5A; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family.
  
 
 
 0.717
smc
Chromosome segregation protein SMC; Required for chromosome condensation and partitioning. Belongs to the SMC family.
 
 
 0.708
rps3ae
PFAM: ribosomal protein S3Ae; KEGG: mbu:Mbur_2336 30S ribosomal protein S3Ae; Belongs to the eukaryotic ribosomal protein eS1 family.
  
   0.704
pheT
TIGRFAM: phenylalanyl-tRNA synthetase, beta subunit; KEGG: mma:MM_2812 phenylalanyl-tRNA synthetase subunit beta; PFAM: tRNA synthetase B5; B3/4 domain protein.
 
   
 0.677
Your Current Organism:
Methanohalobium evestigatum
NCBI taxonomy Id: 644295
Other names: M. evestigatum Z-7303, Methanohalobium evestigatum Z-7303, Methanohalobium evestigatum str. Z-7303, Methanohalobium evestigatum strain Z-7303
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