STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADI74808.1PFAM: Protein of unknown function DUF1288; KEGG: mbu:Mbur_1393 hypothetical protein. (248 aa)    
Predicted Functional Partners:
priS
DNA primase, small subunit; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. [...]
 
   
 0.901
rpl44e
Ribosomal protein L44E; Binds to the 23S rRNA.
 
    0.794
ADI74875.1
PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; KEGG: mac:MA0823 ss-DNA-specific exonuclease.
 
 
 
 0.775
ADI73136.1
PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; KEGG: mbu:Mbur_2340 phosphoesterase, RecJ-like protein.
 
 
 
 0.763
rps27e
PFAM: Ribosomal protein S27E; KEGG: mma:MM_1808 30S ribosomal protein S27e.
 
     0.715
ADI73998.1
PFAM: PRC-barrel domain protein; KEGG: mbu:Mbur_1465 PRC-barrel protein.
  
     0.702
ADI74741.1
PFAM: Protein of unknown function DUF1621; KEGG: mbu:Mbur_0188 hypothetical protein.
  
    0.701
ADI74173.1
KEGG: mbu:Mbur_1577 hypothetical protein.
  
     0.684
pelA
Translation factor pelota; May function in recognizing stalled ribosomes, interact with stem-loop structures in stalled mRNA molecules, and effect endonucleolytic cleavage of the mRNA. May play a role in the release non-functional ribosomes and degradation of damaged mRNAs. Has endoribonuclease activity.
 
     0.680
pcn
Proliferating cell nuclear antigen PcnA; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication.
 
  
 0.674
Your Current Organism:
Methanohalobium evestigatum
NCBI taxonomy Id: 644295
Other names: M. evestigatum Z-7303, Methanohalobium evestigatum Z-7303, Methanohalobium evestigatum str. Z-7303, Methanohalobium evestigatum strain Z-7303
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.