Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
rpl44eRibosomal protein L44E; Binds to the 23S rRNA. (92 aa)    
Predicted Functional Partners:
rpl31e
PFAM: Ribosomal protein L31e; KEGG: mbu:Mbur_0114 50S ribosomal protein L31e; Belongs to the ribosomal protein L31e family.
  
 0.999
rpl40e
KEGG: mac:MA3970 50S ribosomal protein L40e; Belongs to the eukaryotic ribosomal protein eL40 family.
  
 0.999
rpl18
Ribosomal protein L18P/L5E; This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.
  
 0.998
rpl24e
Ribosomal protein L24E; Binds to the 23S rRNA.
   
 0.998
rps27e
PFAM: Ribosomal protein S27E; KEGG: mma:MM_1808 30S ribosomal protein S27e.
 
 
 0.998
rpl19e
Ribosomal protein L19e; Binds to the 23S rRNA; Belongs to the eukaryotic ribosomal protein eL19 family.
  
 0.997
rpl32e
PFAM: Ribosomal protein L32e; KEGG: mbu:Mbur_0018 50S ribosomal protein L32e; Belongs to the eukaryotic ribosomal protein eL32 family.
  
 0.997
rpl22
Ribosomal protein L22; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.
   
 0.997
rpl21e
PFAM: Ribosomal protein L21e; KEGG: mbu:Mbur_0905 50S ribosomal protein L21e; Belongs to the eukaryotic ribosomal protein eL21 family.
 
 0.997
rpl18e
PFAM: ribosomal protein L15; KEGG: mbu:Mbur_2388 50S ribosomal protein L18e; Belongs to the eukaryotic ribosomal protein eL18 family.
  
 0.996
Your Current Organism:
Methanohalobium evestigatum
NCBI taxonomy Id: 644295
Other names: M. evestigatum Z-7303, Methanohalobium evestigatum Z-7303, Methanohalobium evestigatum str. Z-7303, Methanohalobium evestigatum strain Z-7303
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