Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
secEProtein translocase SEC61 complex, gamma subunit; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. (69 aa)    
Predicted Functional Partners:
spt5
NusG antitermination factor; Stimulates transcription elongation; Belongs to the archaeal Spt5 family.
 
  
 0.975
rpl11
Ribosomal protein L11-like protein; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors; Belongs to the universal ribosomal protein uL11 family.
  
   0.971
secY
Preprotein translocase, SecY subunit; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.
  
 
 0.967
rpl31e
PFAM: Ribosomal protein L31e; KEGG: mbu:Mbur_0114 50S ribosomal protein L31e; Belongs to the ribosomal protein L31e family.
  
   0.929
rpl18a
PFAM: Ribosomal LX protein; KEGG: mba:Mbar_A0460 50S ribosomal protein LX.
 
   0.927
rpl44e
Ribosomal protein L44E; Binds to the 23S rRNA.
  
   0.915
rpl32e
PFAM: Ribosomal protein L32e; KEGG: mbu:Mbur_0018 50S ribosomal protein L32e; Belongs to the eukaryotic ribosomal protein eL32 family.
  
   0.894
rps19e
Ribosomal protein S19e; May be involved in maturation of the 30S ribosomal subunit. Belongs to the eukaryotic ribosomal protein eS19 family.
  
   0.890
rps24e
PFAM: Ribosomal protein S24e; KEGG: mma:MM_0599 30S ribosomal protein S24e; Belongs to the eukaryotic ribosomal protein eS24 family.
  
 
 0.888
rpl10
Ribosomal protein L10; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family.
  
   0.888
Your Current Organism:
Methanohalobium evestigatum
NCBI taxonomy Id: 644295
Other names: M. evestigatum Z-7303, Methanohalobium evestigatum Z-7303, Methanohalobium evestigatum str. Z-7303, Methanohalobium evestigatum strain Z-7303
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