Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADI74953.1PFAM: chromosome segregation and condensation protein ScpA; KEGG: mbu:Mbur_1498 condensin subunit ScpA. (287 aa)    
Predicted Functional Partners:
ADI74952.1
KEGG: mbu:Mbur_1497 condensin subunit ScpB; TIGRFAM: segregation and condensation protein B; PFAM: chromosome segregation and condensation protein ScpB.
 
 
 0.999
smc
Chromosome segregation protein SMC; Required for chromosome condensation and partitioning. Belongs to the SMC family.
 
   
 0.960
ADI74955.1
KEGG: mbu:Mbur_1500 hypothetical protein.
       0.923
rad50
SMC domain protein; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50/Mre11 complex; Belongs to the SMC family. RAD50 subfamily.
     
 0.786
ADI73649.1
PFAM: DNA topoisomerase type IA central domain protein; TOPRIM domain protein; DNA topoisomerase type IA zn finger domain protein; KEGG: mbu:Mbur_0705 DNA topoisomerase; SMART: DNA topoisomerase I DNA-binding; DNA topoisomerase I ATP-binding; Toprim sub domain protein.
  
  
 0.759
ADI74774.1
PFAM: sodium/hydrogen exchanger; TrkA-N domain protein; TrkA-C domain protein; KEGG: mbu:Mbur_1363 sodium/hydrogen exchanger.
 
     0.677
ADI74508.1
Peptidase M50; KEGG: mbu:Mbur_0248 peptidase M50; PFAM: peptidase M50; PDZ/DHR/GLGF domain protein; SMART: PDZ/DHR/GLGF domain protein.
 
  
 0.664
mre11
Metallophosphoesterase; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity. Belongs to the MRE11/RAD32 family.
     
 0.641
ADI74948.1
PFAM: glycosyl transferase family 2; KEGG: mbu:Mbur_1495 glycosyl transferase family protein.
  
    0.612
ADI74389.1
PFAM: asparagine synthase; KEGG: mbu:Mbur_0465 asparagine synthase.
       0.599
Your Current Organism:
Methanohalobium evestigatum
NCBI taxonomy Id: 644295
Other names: M. evestigatum Z-7303, Methanohalobium evestigatum Z-7303, Methanohalobium evestigatum str. Z-7303, Methanohalobium evestigatum strain Z-7303
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