| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ADI73046.1 | ADI74988.1 | Metev_0115 | Metev_2162 | PFAM: protein of unknown function DUF167; KEGG: mac:MA4097 hypothetical protein; Belongs to the UPF0235 family. | PFAM: Radical SAM domain protein; KEGG: mba:Mbar_A2775 MoaA/NifB/PqqE family protein. | 0.571 |
| ADI73190.1 | ADI74988.1 | Metev_0262 | Metev_2162 | Geranylgeranyl reductase; Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3- diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di- O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains. | PFAM: Radical SAM domain protein; KEGG: mba:Mbar_A2775 MoaA/NifB/PqqE family protein. | 0.569 |
| ADI73190.1 | carS | Metev_0262 | Metev_0876 | Geranylgeranyl reductase; Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3- diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di- O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains. | Protein of unknown function DUF46; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids. | 0.959 |
| ADI73655.1 | ADI74988.1 | Metev_0754 | Metev_2162 | PFAM: Methyltransferase type 11; KEGG: sfu:Sfum_0266 methyltransferase type 11. | PFAM: Radical SAM domain protein; KEGG: mba:Mbar_A2775 MoaA/NifB/PqqE family protein. | 0.456 |
| ADI74557.1 | ADI74988.1 | Metev_1719 | Metev_2162 | PFAM: Protein of unknown function UPF0147; KEGG: mbu:Mbur_0922 hypothetical protein; Belongs to the UPF0147 family. | PFAM: Radical SAM domain protein; KEGG: mba:Mbar_A2775 MoaA/NifB/PqqE family protein. | 0.571 |
| ADI74988.1 | ADI73046.1 | Metev_2162 | Metev_0115 | PFAM: Radical SAM domain protein; KEGG: mba:Mbar_A2775 MoaA/NifB/PqqE family protein. | PFAM: protein of unknown function DUF167; KEGG: mac:MA4097 hypothetical protein; Belongs to the UPF0235 family. | 0.571 |
| ADI74988.1 | ADI73190.1 | Metev_2162 | Metev_0262 | PFAM: Radical SAM domain protein; KEGG: mba:Mbar_A2775 MoaA/NifB/PqqE family protein. | Geranylgeranyl reductase; Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3- diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di- O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains. | 0.569 |
| ADI74988.1 | ADI73655.1 | Metev_2162 | Metev_0754 | PFAM: Radical SAM domain protein; KEGG: mba:Mbar_A2775 MoaA/NifB/PqqE family protein. | PFAM: Methyltransferase type 11; KEGG: sfu:Sfum_0266 methyltransferase type 11. | 0.456 |
| ADI74988.1 | ADI74557.1 | Metev_2162 | Metev_1719 | PFAM: Radical SAM domain protein; KEGG: mba:Mbar_A2775 MoaA/NifB/PqqE family protein. | PFAM: Protein of unknown function UPF0147; KEGG: mbu:Mbur_0922 hypothetical protein; Belongs to the UPF0147 family. | 0.571 |
| ADI74988.1 | ADI74989.1 | Metev_2162 | Metev_2163 | PFAM: Radical SAM domain protein; KEGG: mba:Mbar_A2775 MoaA/NifB/PqqE family protein. | KEGG: mba:Mbar_A0506 ArsR family transcriptional regulator; PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR. | 0.484 |
| ADI74988.1 | carS | Metev_2162 | Metev_0876 | PFAM: Radical SAM domain protein; KEGG: mba:Mbar_A2775 MoaA/NifB/PqqE family protein. | Protein of unknown function DUF46; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids. | 0.642 |
| ADI74989.1 | ADI74988.1 | Metev_2163 | Metev_2162 | KEGG: mba:Mbar_A0506 ArsR family transcriptional regulator; PFAM: regulatory protein ArsR; SMART: regulatory protein ArsR. | PFAM: Radical SAM domain protein; KEGG: mba:Mbar_A2775 MoaA/NifB/PqqE family protein. | 0.484 |
| carS | ADI73190.1 | Metev_0876 | Metev_0262 | Protein of unknown function DUF46; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids. | Geranylgeranyl reductase; Is involved in the reduction of 2,3- digeranylgeranylglycerophospholipids (unsaturated archaeols) into 2,3- diphytanylglycerophospholipids (saturated archaeols) in the biosynthesis of archaeal membrane lipids. Catalyzes the formation of archaetidic acid (2,3-di-O-phytanyl-sn-glyceryl phosphate) from 2,3-di- O-geranylgeranylglyceryl phosphate (DGGGP) via the hydrogenation of each double bond of the isoprenoid chains. | 0.959 |
| carS | ADI74988.1 | Metev_0876 | Metev_2162 | Protein of unknown function DUF46; Catalyzes the formation of CDP-2,3-bis-(O-geranylgeranyl)-sn- glycerol (CDP-archaeol) from 2,3-bis-(O-geranylgeranyl)-sn-glycerol 1- phosphate (DGGGP) and CTP. This reaction is the third ether-bond- formation step in the biosynthesis of archaeal membrane lipids. | PFAM: Radical SAM domain protein; KEGG: mba:Mbar_A2775 MoaA/NifB/PqqE family protein. | 0.642 |