Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ADI74990.1Transcriptional regulator NikR, CopG family; Transcriptional regulator; Belongs to the transcriptional regulatory CopG/NikR family. (140 aa)    
Predicted Functional Partners:
purC
TIGRFAM: phosphoribosylaminoimidazole-succinocarboxamide synthase; KEGG: mac:MA4063 phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM: SAICAR synthetase.
       0.626
ADI73440.1
TIGRFAM: biotin/acetyl-CoA-carboxylase ligase; KEGG: mba:Mbar_A1588 biotin--(acetyl-CoA-carboxylase) synthetase; PFAM: biotin/lipoate A/B protein ligase; Helix-turn-helix type 11 domain protein; biotin protein ligase domain protein.
     
 0.575
ADI74914.1
KEGG: mma:MM_1334 zinc ABC transporter, ATP-binding protein; PFAM: ABC transporter related; SMART: AAA ATPase.
     
 0.490
ADI74725.1
PFAM: cobalamin (vitamin B12) biosynthesis CbiM protein; KEGG: tye:THEYE_A1920 CbiM.
 
   
 0.448
ADI74913.1
PFAM: ABC-3 protein; KEGG: mba:Mbar_A0996 zinc ABC transporter, permease protein.
     
 0.440
ADI74915.1
PFAM: periplasmic solute binding protein; KEGG: mbu:Mbur_1015 solute binding protein.
       0.400
Your Current Organism:
Methanohalobium evestigatum
NCBI taxonomy Id: 644295
Other names: M. evestigatum Z-7303, Methanohalobium evestigatum Z-7303, Methanohalobium evestigatum str. Z-7303, Methanohalobium evestigatum strain Z-7303
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.