Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ADI75002.1PFAM: protein of unknown function DUF111; KEGG: mma:MM_1617 hypothetical protein; Belongs to the LarC family. (399 aa)    
Predicted Functional Partners:
ADI73351.1
PFAM: 1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase; KEGG: mmp:MMP0809 phosphoribosylaminoimidazole carboxylase related protein.
 
  
 0.962
ADI74705.1
KEGG: mpl:Mpal_1151 PP-loop domain-containing protein.
  
 0.909
ADI74378.1
PFAM: Protein of unknown function DUF2088; KEGG: mac:MA1313 hypothetical protein.
 
  
 0.694
radB
DNA repair and recombination protein RadB; Involved in DNA repair and in homologous recombination. May regulate the cleavage reactions of the branch-structured DNA. Has a very weak ATPase activity that is not stimulated by DNA. Binds DNA but does not promote DNA strands exchange.
       0.571
ADI75003.1
SMART: AAA ATPase; TIGRFAM: AAA family ATPase, CDC48 subfamily; KEGG: mbu:Mbur_2036 AAA family ATPase, CDC48 subfamily protein; PFAM: AAA ATPase central domain protein; AAA ATPase VAT domain protein; cell division protein 48 CDC48 domain 2.
       0.562
ADI73338.1
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: mem:Memar_0224 4Fe-4S ferredoxin iron-sulfur binding domain-containing protein.
 
    0.542
ADI73587.1
Protein of unknown function DUF127; Specifically catalyzes the AdoMet-dependent 2'-O-ribose methylation of cytidine at position 56 in tRNAs; Belongs to the aTrm56 family.
       0.496
ADI75004.1
PFAM: PRC-barrel domain protein; KEGG: mbu:Mbur_2035 PRC-barrel protein.
       0.493
queC
exsB protein; Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)). Belongs to the QueC family.
       0.463
ADI75001.1
PFAM: deoxyribonuclease/rho motif-related TRAM; KEGG: mbu:Mbur_0304 hypothetical protein.
       0.463
Your Current Organism:
Methanohalobium evestigatum
NCBI taxonomy Id: 644295
Other names: M. evestigatum Z-7303, Methanohalobium evestigatum Z-7303, Methanohalobium evestigatum str. Z-7303, Methanohalobium evestigatum strain Z-7303
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