Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADI75026.1Rieske (2Fe-2S) iron-sulfur domain protein; KEGG: mpd:MCP_0975 hypothetical protein; manually curated; PFAM: Rieske [2Fe-2S] iron-sulphur domain. (106 aa)    
Predicted Functional Partners:
ADI75024.1
KEGG: mpd:MCP_0977 hypothetical protein.
 
    0.937
ADI73448.1
PFAM: nitrite and sulphite reductase 4Fe-4S region; nitrite/sulfite reductase hemoprotein beta-component ferrodoxin domain protein; KEGG: mbu:Mbur_1482 nitrite and sulphite reductase, 4Fe-4S subunit.
 
  
 0.933
ADI75025.1
PFAM: glutaredoxin; KEGG: mpd:MCP_0976 putative glutaredoxin.
  
  
 0.924
ADI72962.1
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; pyridine nucleotide-disulphide oxidoreductase dimerisation region; KEGG: mbu:Mbur_1767 FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
 
 
 0.686
ADI73887.1
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: pas:Pars_0912 FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
 
 
 0.673
ADI75022.1
PFAM: ABC-2 type transporter; KEGG: mbu:Mbur_1716 ABC transporter, inner membrane subunit.
 
     0.628
ADI75023.1
Manually curated; PFAM: ABC transporter related; KEGG: mbu:Mbur_1717 ABC transporter, ATPase subunit; SMART: AAA ATPase.
       0.574
ADI73230.1
KEGG: mma:MM_0307 uroporphyrin-III C-methyltransferase; TIGRFAM: uroporphyrin-III C-methyltransferase; PFAM: Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; Belongs to the precorrin methyltransferase family.
  
  
 0.572
ADI75027.1
KEGG: nmr:Nmar_1096 hypothetical protein.
       0.514
cbiX
Cobalamin (vitamin B12) biosynthesis CbiX protein; Catalyzes the insertion of Co(2+) into sirohydrochlorin as part of the anaerobic pathway to cobalamin biosynthesis. Involved in the biosynthesis of the unique nickel-containing tetrapyrrole coenzyme F430, the prosthetic group of methyl-coenzyme M reductase (MCR), which plays a key role in methanogenesis and anaerobic methane oxidation. Catalyzes the insertion of Ni(2+) into sirohydrochlorin to yield Ni- sirohydrochlorin.
  
  
 0.509
Your Current Organism:
Methanohalobium evestigatum
NCBI taxonomy Id: 644295
Other names: M. evestigatum Z-7303, Methanohalobium evestigatum Z-7303, Methanohalobium evestigatum str. Z-7303, Methanohalobium evestigatum strain Z-7303
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