Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ADI75058.1PFAM: Aldehyde Dehydrogenase; KEGG: mbu:Mbur_1940 aldehyde dehydrogenase. (455 aa)    
Predicted Functional Partners:
fumC
Fumarate lyase; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
 0.686
ADI74312.1
KEGG: mma:MM_1528 aconitate hydratase; TIGRFAM: aconitate hydratase 1; PFAM: aconitate hydratase domain protein.
  
 0.671
ADI75059.1
KEGG: mbu:Mbur_0887 hypothetical protein.
       0.628
ADI75060.1
KEGG: mac:MA0812 hypothetical protein.
       0.615
ADI73783.1
SMART: AAA ATPase; TIGRFAM: peptidase S16, Lon-like protease; KEGG: mbu:Mbur_0880 ATP-dependent protease Lon; PFAM: peptidase S16 lon domain protein; magnesium chelatase ChlI subunit; Belongs to the peptidase S16 family.
    
 0.583
ADI74389.1
PFAM: asparagine synthase; KEGG: mbu:Mbur_0465 asparagine synthase.
  
 
 0.582
ADI74774.1
PFAM: sodium/hydrogen exchanger; TrkA-N domain protein; TrkA-C domain protein; KEGG: mbu:Mbur_1363 sodium/hydrogen exchanger.
  
  
 0.564
ADI73999.1
KEGG: mma:MM_1966 malate dehydrogenase; TIGRFAM: malate dehydrogenase, NAD-dependent; PFAM: Lactate/malate dehydrogenase; Belongs to the LDH/MDH superfamily.
  
 0.561
ADI74641.1
Agmatinase; KEGG: mbu:Mbur_1896 agmatinase; TIGRFAM: agmatinase; PFAM: Arginase/agmatinase/formiminoglutamase; Belongs to the arginase family.
  
 
 0.540
rps2
Ribosomal protein S2; KEGG: mbu:Mbur_2393 30S ribosomal protein S2; TIGRFAM: ribosomal protein S2; PFAM: ribosomal protein S2; Belongs to the universal ribosomal protein uS2 family.
  
 0.529
Your Current Organism:
Methanohalobium evestigatum
NCBI taxonomy Id: 644295
Other names: M. evestigatum Z-7303, Methanohalobium evestigatum Z-7303, Methanohalobium evestigatum str. Z-7303, Methanohalobium evestigatum strain Z-7303
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