STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ADI75070.1hydroxymethylglutaryl-CoA synthase; KEGG: mbu:Mbur_1932 hypothetical protein; TIGRFAM: hydroxymethylglutaryl-CoA synthase; PFAM: 3-Oxoacyl-[acyl-carrier-protein (ACP)] synthase III domain protein; Belongs to the thiolase-like superfamily. UPF0219 family. (349 aa)    
Predicted Functional Partners:
ADI74224.1
KEGG: mbu:Mbur_1098 3-hydroxy-3-methylglutaryl-coenzyme A reductase; TIGRFAM: 3-hydroxy-3-methylglutaryl Coenzyme A reductase; PFAM: hydroxymethylglutaryl-coenzyme A reductase; Belongs to the HMG-CoA reductase family.
 
 0.999
ADI75069.1
KEGG: mbu:Mbur_1933 acetyl-CoA acetyltransferase.
 
 0.999
ADI75068.1
PFAM: protein of unknown function DUF35; KEGG: mbu:Mbur_1934 hypothetical protein.
 
 
 0.997
ADI75071.1
KEGG: mbu:Mbur_1931 XRE family transcriptional regulator; PFAM: helix-turn-helix domain protein; SMART: helix-turn-helix domain protein.
 
    0.933
ADI74670.1
KEGG: mbu:Mbur_2155 pyruvate ferredoxin oxidoreductase subunit gamma; TIGRFAM: pyruvate/ketoisovalerate oxidoreductase, gamma subunit; PFAM: Pyruvate/ketoisovalerate oxidoreductase.
    
 0.914
ADI74480.1
TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit; KEGG: mbu:Mbur_0889 2-oxoglutarate ferredoxin oxidoreductase subunit beta; PFAM: thiamine pyrophosphate protein domain protein TPP-binding.
    
 0.906
ADI74667.1
PFAM: thiamine pyrophosphate protein domain protein TPP-binding; KEGG: mma:MM_1339 pyruvate synthase beta subunit.
    
 0.906
ADI74481.1
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Pyruvate/ketoisovalerate oxidoreductase; KEGG: mbu:Mbur_0890 pyruvate flavodoxin/ferredoxin oxidoreductase-like protein.
    
  0.901
ADI74668.1
PFAM: pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; Transketolase domain protein; KEGG: mbu:Mbur_2157 pyruvate ferredoxin oxidoreductase, alpha subunit.
    
  0.901
ADI74669.1
KEGG: mbu:Mbur_2156 pyruvate ferredoxin oxidoreductase, delta subunit; TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase, delta subunit; PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein.
    
  0.901
Your Current Organism:
Methanohalobium evestigatum
NCBI taxonomy Id: 644295
Other names: M. evestigatum Z-7303, Methanohalobium evestigatum Z-7303, Methanohalobium evestigatum str. Z-7303, Methanohalobium evestigatum strain Z-7303
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