STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GGTG_07891Formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily. (442 aa)    
Predicted Functional Partners:
GGTG_09423
S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde.
     
 0.950
GGTG_03403
Formyltetrahydrofolate deformylase.
    
  0.901
GGTG_00246
Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites.
   
 
  0.900
GGTG_04526
Tryptophan synthase.
    
  0.856
GGTG_01707
Malate dehydrogenase.
  
 0.826
GGTG_03204
Malate dehydrogenase.
  
 0.826
GGTG_11622
Malate synthase; Belongs to the malate synthase family.
   
 
 0.813
GGTG_09174
Uncharacterized protein.
  
 
 0.804
GGTG_11621
Fumarate hydratase.
  
 
 0.794
GGTG_00528
NADP-dependent malic enzyme.
    
 0.778
Your Current Organism:
Gaeumannomyces tritici
NCBI taxonomy Id: 644352
Other names: G. tritici R3-111a-1, Gaeumannomyces graminis var. tritici R3-111a-1, Gaeumannomyces tritici R3-111a-1
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