STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EGD56911.1Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. (333 aa)    
Predicted Functional Partners:
EGD56907.1
Ribonucleotide-diphosphate reductase subunit alpha; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides.
 
 0.999
nrdI
Ribonucleotide reductase stimulatory protein; Probably involved in ribonucleotide reductase function.
 
 0.998
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
     
 0.942
ndk
Mulitfunctional nucleoside diphosphate kinase/apyrimidinic endonuclease/3'-phosphodiesterase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
     
 0.933
EGD53204.1
Fatty acid synthase; COG0331 (acyl-carrier-protein) S-malonyltransferase.
    
 0.933
gmk
Guanylate kinase; Essential for recycling GMP and indirectly, cGMP.
     
 0.930
EGD54834.1
COG0208 Ribonucleotide reductase, beta subunit.
     
 0.902
EGD56905.1
Glutaredoxin-like protein NrdH; COG0695 Glutaredoxin and related proteins.
 
  
 0.899
EGD57167.1
Glutaredoxin-like protein NrdH; COG0695 Glutaredoxin and related proteins.
 
  
 0.899
tmk
Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family.
   
 
 0.875
Your Current Organism:
Gordonia neofelifaecis
NCBI taxonomy Id: 644548
Other names: G. neofelifaecis NRRL B-59395, Gordonia neofelifaecis AD-6, Gordonia neofelifaecis NRRL B-59395, Gordonia neofelifaecis str. NRRL B-59395, Gordonia neofelifaecis strain NRRL B-59395, Gordonia sp. AD-6
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