node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
EGD54869.1 | EGD56465.1 | SCNU_11700 | SCNU_02902 | HSP90 family protein; COG0326 Molecular chaperone, HSP90 family. | Hypothetical protein. | 0.991 |
EGD54869.1 | dnaJ | SCNU_11700 | SCNU_01635 | HSP90 family protein; COG0326 Molecular chaperone, HSP90 family. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.981 |
EGD54869.1 | dnaK | SCNU_11700 | SCNU_10581 | HSP90 family protein; COG0326 Molecular chaperone, HSP90 family. | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.991 |
EGD54869.1 | groEL | SCNU_11700 | SCNU_17148 | HSP90 family protein; COG0326 Molecular chaperone, HSP90 family. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.939 |
EGD54869.1 | grpE | SCNU_11700 | SCNU_10576 | HSP90 family protein; COG0326 Molecular chaperone, HSP90 family. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.722 |
EGD54967.1 | EGD56465.1 | SCNU_10566 | SCNU_02902 | Regulatory protein MerR; COG0789 Predicted transcriptional regulators. | Hypothetical protein. | 0.694 |
EGD54967.1 | dnaJ | SCNU_10566 | SCNU_01635 | Regulatory protein MerR; COG0789 Predicted transcriptional regulators. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.936 |
EGD54967.1 | dnaK | SCNU_10566 | SCNU_10581 | Regulatory protein MerR; COG0789 Predicted transcriptional regulators. | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. | 0.990 |
EGD54967.1 | groEL | SCNU_10566 | SCNU_17148 | Regulatory protein MerR; COG0789 Predicted transcriptional regulators. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.626 |
EGD54967.1 | grpE | SCNU_10566 | SCNU_10576 | Regulatory protein MerR; COG0789 Predicted transcriptional regulators. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.983 |
EGD54967.1 | hrcA | SCNU_10566 | SCNU_01630 | Regulatory protein MerR; COG0789 Predicted transcriptional regulators. | Heat-inducible transcription repressor; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.822 |
EGD56465.1 | EGD54869.1 | SCNU_02902 | SCNU_11700 | Hypothetical protein. | HSP90 family protein; COG0326 Molecular chaperone, HSP90 family. | 0.991 |
EGD56465.1 | EGD54967.1 | SCNU_02902 | SCNU_10566 | Hypothetical protein. | Regulatory protein MerR; COG0789 Predicted transcriptional regulators. | 0.694 |
EGD56465.1 | dnaJ | SCNU_02902 | SCNU_01635 | Hypothetical protein. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.992 |
EGD56465.1 | groEL | SCNU_02902 | SCNU_17148 | Hypothetical protein. | Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. | 0.968 |
EGD56465.1 | grpE | SCNU_02902 | SCNU_10576 | Hypothetical protein. | GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...] | 0.989 |
EGD56465.1 | hrcA | SCNU_02902 | SCNU_01630 | Hypothetical protein. | Heat-inducible transcription repressor; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.841 |
EGD56465.1 | htpG | SCNU_02902 | SCNU_18452 | Hypothetical protein. | Heat shock protein 90; Molecular chaperone. Has ATPase activity. | 0.991 |
EGD57038.1 | dnaJ | SCNU_01640 | SCNU_01635 | 16S ribosomal RNA methyltransferase RsmE; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.941 |
EGD57038.1 | hrcA | SCNU_01640 | SCNU_01630 | 16S ribosomal RNA methyltransferase RsmE; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit. | Heat-inducible transcription repressor; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | 0.871 |