STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EGD56504.1COG1045 Serine acetyltransferase. (193 aa)    
Predicted Functional Partners:
EGD56505.1
COG0031 Cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.
 
 0.999
EGD56422.1
Cystathionine beta-synthase; COG0031 Cysteine synthase.
 
 0.981
EGD53369.1
Pyridoxal-phosphate dependent enzyme; COG0031 Cysteine synthase.
  
 0.971
cysS
COG0215 Cysteinyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
 
 
 0.943
mshC
cysteinyl-tRNA synthetase; Catalyzes the ATP-dependent condensation of GlcN-Ins and L- cysteine to form L-Cys-GlcN-Ins; Belongs to the class-I aminoacyl-tRNA synthetase family. MshC subfamily.
 
 
 0.876
EGD56919.1
Phosphoserine phosphatase SerB; COG3830 ACT domain-containing protein.
    
 0.850
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
     
 0.842
glyA-2
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
     
 0.842
thrB
Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.
     
 0.813
EGD56683.1
COG0460 Homoserine dehydrogenase.
     
 0.803
Your Current Organism:
Gordonia neofelifaecis
NCBI taxonomy Id: 644548
Other names: G. neofelifaecis NRRL B-59395, Gordonia neofelifaecis AD-6, Gordonia neofelifaecis NRRL B-59395, Gordonia neofelifaecis str. NRRL B-59395, Gordonia neofelifaecis strain NRRL B-59395, Gordonia sp. AD-6
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