Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EGD55656.1Hypothetical protein; COG0457 FOG: TPR repeat. (380 aa)    
Predicted Functional Partners:
EGD55657.1
Short chain dehydrogenase; COG1028 Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases).
  0.953
EGD55658.1
Hypothetical protein.
 
    0.941
EGD54614.1
Hypothetical protein; COG2319 FOG: WD40 repeat.
    
 0.877
alaS
alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
   
 0.863
EGD54869.1
HSP90 family protein; COG0326 Molecular chaperone, HSP90 family.
   
 0.843
htpG
Heat shock protein 90; Molecular chaperone. Has ATPase activity.
   
 0.843
EGD55659.1
Hypothetical protein; COG0050 GTPases - translation elongation factors.
 
     0.840
ndk
Mulitfunctional nucleoside diphosphate kinase/apyrimidinic endonuclease/3'-phosphodiesterase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
   
  0.839
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 0.839
EGD55655.1
Oxidoreductase; COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases.
 
     0.838
Your Current Organism:
Gordonia neofelifaecis
NCBI taxonomy Id: 644548
Other names: G. neofelifaecis NRRL B-59395, Gordonia neofelifaecis AD-6, Gordonia neofelifaecis NRRL B-59395, Gordonia neofelifaecis str. NRRL B-59395, Gordonia neofelifaecis strain NRRL B-59395, Gordonia sp. AD-6
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.