| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| grpE-1 | pilB | sync_0022 | sync_0021 | Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...] | Type IV pilus assembly protein PilB; Identified by match to protein family HMM PF00437. | 0.602 |
| grpE-1 | pilC | sync_0022 | sync_0019 | Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...] | Type IV pilus assembly protein PilC; Identified by match to protein family HMM PF00482. | 0.580 |
| grpE-1 | pilT | sync_0022 | sync_0020 | Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...] | Twitching motility protein; Identified by similarity to SP:P24559; match to protein family HMM PF00437; match to protein family HMM TIGR01420. | 0.564 |
| gspO | pilB | sync_1709 | sync_0021 | Prepilin peptidase; Identified by similarity to SP:P31712; match to protein family HMM PF01478; match to protein family HMM PF06750. | Type IV pilus assembly protein PilB; Identified by match to protein family HMM PF00437. | 0.907 |
| gspO | pilC | sync_1709 | sync_0019 | Prepilin peptidase; Identified by similarity to SP:P31712; match to protein family HMM PF01478; match to protein family HMM PF06750. | Type IV pilus assembly protein PilC; Identified by match to protein family HMM PF00482. | 0.904 |
| gspO | pilT | sync_1709 | sync_0020 | Prepilin peptidase; Identified by similarity to SP:P31712; match to protein family HMM PF01478; match to protein family HMM PF06750. | Twitching motility protein; Identified by similarity to SP:P24559; match to protein family HMM PF00437; match to protein family HMM TIGR01420. | 0.820 |
| gspO | sync_0659 | sync_1709 | sync_0659 | Prepilin peptidase; Identified by similarity to SP:P31712; match to protein family HMM PF01478; match to protein family HMM PF06750. | Possible pilin; Identified by match to protein family HMM TIGR02532. | 0.724 |
| gspO | sync_0667 | sync_1709 | sync_0667 | Prepilin peptidase; Identified by similarity to SP:P31712; match to protein family HMM PF01478; match to protein family HMM PF06750. | Possible pilin; Identified by match to protein family HMM PF07963; match to protein family HMM TIGR02532. | 0.860 |
| gspO | sync_2158 | sync_1709 | sync_2158 | Prepilin peptidase; Identified by similarity to SP:P31712; match to protein family HMM PF01478; match to protein family HMM PF06750. | Twitching mobility protein PilT; Identified by match to protein family HMM PF00437; match to protein family HMM TIGR01420. | 0.813 |
| gspO | sync_2206 | sync_1709 | sync_2206 | Prepilin peptidase; Identified by similarity to SP:P31712; match to protein family HMM PF01478; match to protein family HMM PF06750. | Conserved hypothetical protein. | 0.676 |
| gspO | sync_2717 | sync_1709 | sync_2717 | Prepilin peptidase; Identified by similarity to SP:P31712; match to protein family HMM PF01478; match to protein family HMM PF06750. | Possible general (type II) secretion pathway protein D precursor; Identified by match to protein family HMM PF00263; match to protein family HMM PF07660; Belongs to the bacterial secretin family. | 0.478 |
| pilB | grpE-1 | sync_0021 | sync_0022 | Type IV pilus assembly protein PilB; Identified by match to protein family HMM PF00437. | Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...] | 0.602 |
| pilB | gspO | sync_0021 | sync_1709 | Type IV pilus assembly protein PilB; Identified by match to protein family HMM PF00437. | Prepilin peptidase; Identified by similarity to SP:P31712; match to protein family HMM PF01478; match to protein family HMM PF06750. | 0.907 |
| pilB | pilC | sync_0021 | sync_0019 | Type IV pilus assembly protein PilB; Identified by match to protein family HMM PF00437. | Type IV pilus assembly protein PilC; Identified by match to protein family HMM PF00482. | 0.998 |
| pilB | pilT | sync_0021 | sync_0020 | Type IV pilus assembly protein PilB; Identified by match to protein family HMM PF00437. | Twitching motility protein; Identified by similarity to SP:P24559; match to protein family HMM PF00437; match to protein family HMM TIGR01420. | 0.853 |
| pilB | sync_0659 | sync_0021 | sync_0659 | Type IV pilus assembly protein PilB; Identified by match to protein family HMM PF00437. | Possible pilin; Identified by match to protein family HMM TIGR02532. | 0.539 |
| pilB | sync_0667 | sync_0021 | sync_0667 | Type IV pilus assembly protein PilB; Identified by match to protein family HMM PF00437. | Possible pilin; Identified by match to protein family HMM PF07963; match to protein family HMM TIGR02532. | 0.967 |
| pilB | sync_2158 | sync_0021 | sync_2158 | Type IV pilus assembly protein PilB; Identified by match to protein family HMM PF00437. | Twitching mobility protein PilT; Identified by match to protein family HMM PF00437; match to protein family HMM TIGR01420. | 0.436 |
| pilB | sync_2206 | sync_0021 | sync_2206 | Type IV pilus assembly protein PilB; Identified by match to protein family HMM PF00437. | Conserved hypothetical protein. | 0.597 |
| pilB | sync_2671 | sync_0021 | sync_2671 | Type IV pilus assembly protein PilB; Identified by match to protein family HMM PF00437. | Identified by match to protein family HMM PF00563; match to protein family HMM PF00990; match to protein family HMM TIGR00254. | 0.677 |