| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| dnaJ-2 | grpE-1 | sync_0023 | sync_0022 | DnaJ protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and Gr [...] | Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...] | 0.963 |
| dnaJ-2 | rsgA | sync_0023 | sync_0025 | DnaJ protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and Gr [...] | Ribosome-associated GTPase YjeQ; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily. | 0.815 |
| dnaJ-2 | sync_0024 | sync_0023 | sync_0024 | DnaJ protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and Gr [...] | Conserved hypothetical protein; Identified by similarity to PIR:AI2111; Belongs to the sulfur carrier protein TusA family. | 0.816 |
| grpE-1 | dnaJ-2 | sync_0022 | sync_0023 | Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...] | DnaJ protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and Gr [...] | 0.963 |
| grpE-1 | rsgA | sync_0022 | sync_0025 | Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...] | Ribosome-associated GTPase YjeQ; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily. | 0.577 |
| grpE-1 | sync_0024 | sync_0022 | sync_0024 | Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...] | Conserved hypothetical protein; Identified by similarity to PIR:AI2111; Belongs to the sulfur carrier protein TusA family. | 0.630 |
| nifS | spl1 | sync_1367 | sync_2644 | Possible cysteine desulfurase (class-V aminotransferase family); Identified by match to protein family HMM PF00266. | NifS-like aminotransferase class-V; Identified by match to protein family HMM PF00266; match to protein family HMM PF01212. | 0.921 |
| nifS | sync_0024 | sync_1367 | sync_0024 | Possible cysteine desulfurase (class-V aminotransferase family); Identified by match to protein family HMM PF00266. | Conserved hypothetical protein; Identified by similarity to PIR:AI2111; Belongs to the sulfur carrier protein TusA family. | 0.759 |
| nifS | sync_0452 | sync_1367 | sync_0452 | Possible cysteine desulfurase (class-V aminotransferase family); Identified by match to protein family HMM PF00266. | Putative molybdopterin biosynthesis protein MoeB; Identified by match to protein family HMM PF00581; match to protein family HMM PF00899; match to protein family HMM PF05237. | 0.984 |
| rsgA | dnaJ-2 | sync_0025 | sync_0023 | Ribosome-associated GTPase YjeQ; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily. | DnaJ protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and Gr [...] | 0.815 |
| rsgA | grpE-1 | sync_0025 | sync_0022 | Ribosome-associated GTPase YjeQ; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily. | Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...] | 0.577 |
| rsgA | sync_0024 | sync_0025 | sync_0024 | Ribosome-associated GTPase YjeQ; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily. | Conserved hypothetical protein; Identified by similarity to PIR:AI2111; Belongs to the sulfur carrier protein TusA family. | 0.816 |
| spl1 | nifS | sync_2644 | sync_1367 | NifS-like aminotransferase class-V; Identified by match to protein family HMM PF00266; match to protein family HMM PF01212. | Possible cysteine desulfurase (class-V aminotransferase family); Identified by match to protein family HMM PF00266. | 0.921 |
| spl1 | sync_0024 | sync_2644 | sync_0024 | NifS-like aminotransferase class-V; Identified by match to protein family HMM PF00266; match to protein family HMM PF01212. | Conserved hypothetical protein; Identified by similarity to PIR:AI2111; Belongs to the sulfur carrier protein TusA family. | 0.759 |
| spl1 | sync_0452 | sync_2644 | sync_0452 | NifS-like aminotransferase class-V; Identified by match to protein family HMM PF00266; match to protein family HMM PF01212. | Putative molybdopterin biosynthesis protein MoeB; Identified by match to protein family HMM PF00581; match to protein family HMM PF00899; match to protein family HMM PF05237. | 0.984 |
| sync_0024 | dnaJ-2 | sync_0024 | sync_0023 | Conserved hypothetical protein; Identified by similarity to PIR:AI2111; Belongs to the sulfur carrier protein TusA family. | DnaJ protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and Gr [...] | 0.816 |
| sync_0024 | grpE-1 | sync_0024 | sync_0022 | Conserved hypothetical protein; Identified by similarity to PIR:AI2111; Belongs to the sulfur carrier protein TusA family. | Co-chaperone GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-depend [...] | 0.630 |
| sync_0024 | nifS | sync_0024 | sync_1367 | Conserved hypothetical protein; Identified by similarity to PIR:AI2111; Belongs to the sulfur carrier protein TusA family. | Possible cysteine desulfurase (class-V aminotransferase family); Identified by match to protein family HMM PF00266. | 0.759 |
| sync_0024 | rsgA | sync_0024 | sync_0025 | Conserved hypothetical protein; Identified by similarity to PIR:AI2111; Belongs to the sulfur carrier protein TusA family. | Ribosome-associated GTPase YjeQ; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit; Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily. | 0.816 |
| sync_0024 | spl1 | sync_0024 | sync_2644 | Conserved hypothetical protein; Identified by similarity to PIR:AI2111; Belongs to the sulfur carrier protein TusA family. | NifS-like aminotransferase class-V; Identified by match to protein family HMM PF00266; match to protein family HMM PF01212. | 0.759 |