| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ksgA | pdxA | sync_1594 | sync_0034 | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 4-hydroxythreonine-4-phosphate dehydrogenase; Identified by match to protein family HMM PF04166; match to protein family HMM TIGR00557; Belongs to the PdxA family. | 0.483 |
| ksgA | sync_0156 | sync_1594 | sync_0156 | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | Polyketide synthase, putative; Identified by match to protein family HMM PF00106; match to protein family HMM PF00107; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02801; match to protein family HMM PF07993; match to protein family HMM TIGR01746. | 0.692 |
| pdxA | ksgA | sync_0034 | sync_1594 | 4-hydroxythreonine-4-phosphate dehydrogenase; Identified by match to protein family HMM PF04166; match to protein family HMM TIGR00557; Belongs to the PdxA family. | Dimethyladenosine transferase; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. | 0.483 |
| pdxA | pdxJ | sync_0034 | sync_1151 | 4-hydroxythreonine-4-phosphate dehydrogenase; Identified by match to protein family HMM PF04166; match to protein family HMM TIGR00557; Belongs to the PdxA family. | Pyridoxal phosphate biosynthetic protein PdxJ; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. | 0.925 |
| pdxA | ribAB | sync_0034 | sync_1383 | 4-hydroxythreonine-4-phosphate dehydrogenase; Identified by match to protein family HMM PF04166; match to protein family HMM TIGR00557; Belongs to the PdxA family. | Riboflavin biosynthesis protein RibA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.522 |
| pdxA | ribD | sync_0034 | sync_0821 | 4-hydroxythreonine-4-phosphate dehydrogenase; Identified by match to protein family HMM PF04166; match to protein family HMM TIGR00557; Belongs to the PdxA family. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.475 |
| pdxA | sync_0045 | sync_0034 | sync_0045 | 4-hydroxythreonine-4-phosphate dehydrogenase; Identified by match to protein family HMM PF04166; match to protein family HMM TIGR00557; Belongs to the PdxA family. | Soluble hydrogenase, tritium exchange subunit, putative; Identified by similarity to SP:P14776; match to protein family HMM PF00266. | 0.499 |
| pdxA | sync_0156 | sync_0034 | sync_0156 | 4-hydroxythreonine-4-phosphate dehydrogenase; Identified by match to protein family HMM PF04166; match to protein family HMM TIGR00557; Belongs to the PdxA family. | Polyketide synthase, putative; Identified by match to protein family HMM PF00106; match to protein family HMM PF00107; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02801; match to protein family HMM PF07993; match to protein family HMM TIGR01746. | 0.421 |
| pdxA | thrC | sync_0034 | sync_2943 | 4-hydroxythreonine-4-phosphate dehydrogenase; Identified by match to protein family HMM PF04166; match to protein family HMM TIGR00557; Belongs to the PdxA family. | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. | 0.902 |
| pdxA | wcaG-1 | sync_0034 | sync_0035 | 4-hydroxythreonine-4-phosphate dehydrogenase; Identified by match to protein family HMM PF04166; match to protein family HMM TIGR00557; Belongs to the PdxA family. | NAD dependent epimerase/dehydratase; Identified by match to protein family HMM PF01370. | 0.491 |
| pdxJ | pdxA | sync_1151 | sync_0034 | Pyridoxal phosphate biosynthetic protein PdxJ; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. | 4-hydroxythreonine-4-phosphate dehydrogenase; Identified by match to protein family HMM PF04166; match to protein family HMM TIGR00557; Belongs to the PdxA family. | 0.925 |
| pdxJ | ribAB | sync_1151 | sync_1383 | Pyridoxal phosphate biosynthetic protein PdxJ; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. | Riboflavin biosynthesis protein RibA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.619 |
| pdxJ | ribD | sync_1151 | sync_0821 | Pyridoxal phosphate biosynthetic protein PdxJ; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.617 |
| ribAB | pdxA | sync_1383 | sync_0034 | Riboflavin biosynthesis protein RibA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 4-hydroxythreonine-4-phosphate dehydrogenase; Identified by match to protein family HMM PF04166; match to protein family HMM TIGR00557; Belongs to the PdxA family. | 0.522 |
| ribAB | pdxJ | sync_1383 | sync_1151 | Riboflavin biosynthesis protein RibA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | Pyridoxal phosphate biosynthetic protein PdxJ; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. | 0.619 |
| ribAB | ribD | sync_1383 | sync_0821 | Riboflavin biosynthesis protein RibA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.999 |
| ribAB | sync_0156 | sync_1383 | sync_0156 | Riboflavin biosynthesis protein RibA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | Polyketide synthase, putative; Identified by match to protein family HMM PF00106; match to protein family HMM PF00107; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02801; match to protein family HMM PF07993; match to protein family HMM TIGR01746. | 0.761 |
| ribD | pdxA | sync_0821 | sync_0034 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 4-hydroxythreonine-4-phosphate dehydrogenase; Identified by match to protein family HMM PF04166; match to protein family HMM TIGR00557; Belongs to the PdxA family. | 0.475 |
| ribD | pdxJ | sync_0821 | sync_1151 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Pyridoxal phosphate biosynthetic protein PdxJ; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. | 0.617 |
| ribD | ribAB | sync_0821 | sync_1383 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Riboflavin biosynthesis protein RibA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.999 |