guaA protein (Synechococcus sp. CC9311) - STRING interaction network

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Score

guaA

GMP synthase, glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP. (528 aa)

Predicted Functional Partners:

apt

0.995

argS

0.995

pyrG

0.990

rplK

0.989

tatA

0.982

lysS

0.980

sync_0971

0.980

map

0.980

tuf

0.976

rplA

0.973

Your Current Organism:

Synechococcus sp. CC9311

NCBI taxonomy Id: 64471
Other names: S. sp. CC9311

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
apt	guaA	sync_1226	sync_0047	Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	GMP synthase, glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP.	0.995
apt	pyrG	sync_1226	sync_2858	Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.	0.490
argS	guaA	sync_2667	sync_0047	arginyl-tRNA synthetase; Identified by match to protein family HMM PF00750; match to protein family HMM PF03485; match to protein family HMM PF05746; match to protein family HMM TIGR00456.	GMP synthase, glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP.	0.995
argS	lysS	sync_2667	sync_0116	arginyl-tRNA synthetase; Identified by match to protein family HMM PF00750; match to protein family HMM PF03485; match to protein family HMM PF05746; match to protein family HMM TIGR00456.	lysyl-tRNA synthetase; Identified by match to protein family HMM PF00152; match to protein family HMM PF01336; match to protein family HMM TIGR00499; Belongs to the class-II aminoacyl-tRNA synthetase family.	0.865
argS	pyrG	sync_2667	sync_2858	arginyl-tRNA synthetase; Identified by match to protein family HMM PF00750; match to protein family HMM PF03485; match to protein family HMM PF05746; match to protein family HMM TIGR00456.	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.	0.820
argS	rplA	sync_2667	sync_2726	arginyl-tRNA synthetase; Identified by match to protein family HMM PF00750; match to protein family HMM PF03485; match to protein family HMM PF05746; match to protein family HMM TIGR00456.	Ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.	0.478
argS	rplK	sync_2667	sync_2727	arginyl-tRNA synthetase; Identified by match to protein family HMM PF00750; match to protein family HMM PF03485; match to protein family HMM PF05746; match to protein family HMM TIGR00456.	Ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.	0.512
guaA	apt	sync_0047	sync_1226	GMP synthase, glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP.	Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	0.995
guaA	argS	sync_0047	sync_2667	GMP synthase, glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP.	arginyl-tRNA synthetase; Identified by match to protein family HMM PF00750; match to protein family HMM PF03485; match to protein family HMM PF05746; match to protein family HMM TIGR00456.	0.995
guaA	lysS	sync_0047	sync_0116	GMP synthase, glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP.	lysyl-tRNA synthetase; Identified by match to protein family HMM PF00152; match to protein family HMM PF01336; match to protein family HMM TIGR00499; Belongs to the class-II aminoacyl-tRNA synthetase family.	0.980
guaA	map	sync_0047	sync_2170	GMP synthase, glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP.	Methionine aminopeptidase, type I; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily.	0.980
guaA	pyrG	sync_0047	sync_2858	GMP synthase, glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP.	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.	0.990
guaA	rplA	sync_0047	sync_2726	GMP synthase, glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP.	Ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.	0.973
guaA	rplK	sync_0047	sync_2727	GMP synthase, glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP.	Ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.	0.989
guaA	sync_0971	sync_0047	sync_0971	GMP synthase, glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP.	Identified by match to protein family HMM PF00478; match to protein family HMM TIGR01304.	0.980
guaA	tatA	sync_0047	sync_0311	GMP synthase, glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP.	Twin-arginine translocation protein TatA; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.	0.982
guaA	tuf	sync_0047	sync_0381	GMP synthase, glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP.	Translation elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.	0.976
lysS	argS	sync_0116	sync_2667	lysyl-tRNA synthetase; Identified by match to protein family HMM PF00152; match to protein family HMM PF01336; match to protein family HMM TIGR00499; Belongs to the class-II aminoacyl-tRNA synthetase family.	arginyl-tRNA synthetase; Identified by match to protein family HMM PF00750; match to protein family HMM PF03485; match to protein family HMM PF05746; match to protein family HMM TIGR00456.	0.865
lysS	guaA	sync_0116	sync_0047	lysyl-tRNA synthetase; Identified by match to protein family HMM PF00152; match to protein family HMM PF01336; match to protein family HMM TIGR00499; Belongs to the class-II aminoacyl-tRNA synthetase family.	GMP synthase, glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP.	0.980
lysS	pyrG	sync_0116	sync_2858	lysyl-tRNA synthetase; Identified by match to protein family HMM PF00152; match to protein family HMM PF01336; match to protein family HMM TIGR00499; Belongs to the class-II aminoacyl-tRNA synthetase family.	CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.	0.676