| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| argS | gmk | sync_2667 | sync_2153 | arginyl-tRNA synthetase; Identified by match to protein family HMM PF00750; match to protein family HMM PF03485; match to protein family HMM PF05746; match to protein family HMM TIGR00456. | Guanylate kinase, putative; Essential for recycling GMP and indirectly, cGMP. | 0.481 |
| argS | guaA | sync_2667 | sync_0047 | arginyl-tRNA synthetase; Identified by match to protein family HMM PF00750; match to protein family HMM PF03485; match to protein family HMM PF05746; match to protein family HMM TIGR00456. | GMP synthase, glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP. | 0.965 |
| argS | lysS | sync_2667 | sync_0116 | arginyl-tRNA synthetase; Identified by match to protein family HMM PF00750; match to protein family HMM PF03485; match to protein family HMM PF05746; match to protein family HMM TIGR00456. | lysyl-tRNA synthetase; Identified by match to protein family HMM PF00152; match to protein family HMM PF01336; match to protein family HMM TIGR00499; Belongs to the class-II aminoacyl-tRNA synthetase family. | 0.964 |
| argS | pyrG | sync_2667 | sync_2858 | arginyl-tRNA synthetase; Identified by match to protein family HMM PF00750; match to protein family HMM PF03485; match to protein family HMM PF05746; match to protein family HMM TIGR00456. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.830 |
| argS | rplK | sync_2667 | sync_2727 | arginyl-tRNA synthetase; Identified by match to protein family HMM PF00750; match to protein family HMM PF03485; match to protein family HMM PF05746; match to protein family HMM TIGR00456. | Ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. | 0.565 |
| gmk | argS | sync_2153 | sync_2667 | Guanylate kinase, putative; Essential for recycling GMP and indirectly, cGMP. | arginyl-tRNA synthetase; Identified by match to protein family HMM PF00750; match to protein family HMM PF03485; match to protein family HMM PF05746; match to protein family HMM TIGR00456. | 0.481 |
| gmk | guaA | sync_2153 | sync_0047 | Guanylate kinase, putative; Essential for recycling GMP and indirectly, cGMP. | GMP synthase, glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP. | 0.969 |
| gmk | pyrG | sync_2153 | sync_2858 | Guanylate kinase, putative; Essential for recycling GMP and indirectly, cGMP. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.445 |
| gmk | surE | sync_2153 | sync_0795 | Guanylate kinase, putative; Essential for recycling GMP and indirectly, cGMP. | Acid phosphatase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.900 |
| guaA | argS | sync_0047 | sync_2667 | GMP synthase, glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP. | arginyl-tRNA synthetase; Identified by match to protein family HMM PF00750; match to protein family HMM PF03485; match to protein family HMM PF05746; match to protein family HMM TIGR00456. | 0.965 |
| guaA | gmk | sync_0047 | sync_2153 | GMP synthase, glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP. | Guanylate kinase, putative; Essential for recycling GMP and indirectly, cGMP. | 0.969 |
| guaA | lysS | sync_0047 | sync_0116 | GMP synthase, glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP. | lysyl-tRNA synthetase; Identified by match to protein family HMM PF00152; match to protein family HMM PF01336; match to protein family HMM TIGR00499; Belongs to the class-II aminoacyl-tRNA synthetase family. | 0.941 |
| guaA | purH | sync_0047 | sync_0289 | GMP synthase, glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP. | Bifunctional purine biosynthesis protein PurH; Identified by match to protein family HMM PF01808; match to protein family HMM PF02142; match to protein family HMM TIGR00355. | 0.939 |
| guaA | pyrG | sync_0047 | sync_2858 | GMP synthase, glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.954 |
| guaA | rdgB | sync_0047 | sync_0272 | GMP synthase, glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP. | Non-canonical purine NTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.954 |
| guaA | rplK | sync_0047 | sync_2727 | GMP synthase, glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP. | Ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. | 0.946 |
| guaA | surE | sync_0047 | sync_0795 | GMP synthase, glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP. | Acid phosphatase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.965 |
| guaA | sync_0971 | sync_0047 | sync_0971 | GMP synthase, glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP. | Identified by match to protein family HMM PF00478; match to protein family HMM TIGR01304. | 0.985 |
| guaA | tatA | sync_0047 | sync_0311 | GMP synthase, glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP. | Twin-arginine translocation protein TatA; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system. | 0.945 |
| lysS | argS | sync_0116 | sync_2667 | lysyl-tRNA synthetase; Identified by match to protein family HMM PF00152; match to protein family HMM PF01336; match to protein family HMM TIGR00499; Belongs to the class-II aminoacyl-tRNA synthetase family. | arginyl-tRNA synthetase; Identified by match to protein family HMM PF00750; match to protein family HMM PF03485; match to protein family HMM PF05746; match to protein family HMM TIGR00456. | 0.964 |
