| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ahcY | sync_0107 | sync_0108 | sync_0107 | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | Conserved hypothetical protein TIGR00150; Identified by similarity to GB:CAE20312.1; match to protein family HMM PF02367; match to protein family HMM TIGR00150. | 0.641 |
| alr | nnrD | sync_0406 | sync_0760 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | Carbohydrate kinase family protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. In the C-terminal section; belongs to the NnrD/CARKD family. | 0.467 |
| alr | sync_0107 | sync_0406 | sync_0107 | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | Conserved hypothetical protein TIGR00150; Identified by similarity to GB:CAE20312.1; match to protein family HMM PF02367; match to protein family HMM TIGR00150. | 0.461 |
| gcp | sync_0107 | sync_2156 | sync_0107 | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | Conserved hypothetical protein TIGR00150; Identified by similarity to GB:CAE20312.1; match to protein family HMM PF02367; match to protein family HMM TIGR00150. | 0.987 |
| gcp | sync_0541 | sync_2156 | sync_0541 | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | yrdC domain, putative; Identified by match to protein family HMM PF01300; Belongs to the SUA5 family. | 0.757 |
| gcp | sync_2603 | sync_2156 | sync_2603 | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | Identified by match to protein family HMM PF00814. | 0.993 |
| ileS | sync_0107 | sync_0333 | sync_0107 | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | Conserved hypothetical protein TIGR00150; Identified by similarity to GB:CAE20312.1; match to protein family HMM PF02367; match to protein family HMM TIGR00150. | 0.442 |
| miaA | nnrD | sync_0091 | sync_0760 | tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | Carbohydrate kinase family protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. In the C-terminal section; belongs to the NnrD/CARKD family. | 0.497 |
| miaA | sync_0107 | sync_0091 | sync_0107 | tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | Conserved hypothetical protein TIGR00150; Identified by similarity to GB:CAE20312.1; match to protein family HMM PF02367; match to protein family HMM TIGR00150. | 0.485 |
| nnrD | alr | sync_0760 | sync_0406 | Carbohydrate kinase family protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. In the C-terminal section; belongs to the NnrD/CARKD family. | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | 0.467 |
| nnrD | miaA | sync_0760 | sync_0091 | Carbohydrate kinase family protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. In the C-terminal section; belongs to the NnrD/CARKD family. | tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | 0.497 |
| nnrD | sync_0107 | sync_0760 | sync_0107 | Carbohydrate kinase family protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. In the C-terminal section; belongs to the NnrD/CARKD family. | Conserved hypothetical protein TIGR00150; Identified by similarity to GB:CAE20312.1; match to protein family HMM PF02367; match to protein family HMM TIGR00150. | 0.700 |
| sync_0107 | ahcY | sync_0107 | sync_0108 | Conserved hypothetical protein TIGR00150; Identified by similarity to GB:CAE20312.1; match to protein family HMM PF02367; match to protein family HMM TIGR00150. | Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. | 0.641 |
| sync_0107 | alr | sync_0107 | sync_0406 | Conserved hypothetical protein TIGR00150; Identified by similarity to GB:CAE20312.1; match to protein family HMM PF02367; match to protein family HMM TIGR00150. | Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. | 0.461 |
| sync_0107 | gcp | sync_0107 | sync_2156 | Conserved hypothetical protein TIGR00150; Identified by similarity to GB:CAE20312.1; match to protein family HMM PF02367; match to protein family HMM TIGR00150. | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.987 |
| sync_0107 | ileS | sync_0107 | sync_0333 | Conserved hypothetical protein TIGR00150; Identified by similarity to GB:CAE20312.1; match to protein family HMM PF02367; match to protein family HMM TIGR00150. | isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | 0.442 |
| sync_0107 | miaA | sync_0107 | sync_0091 | Conserved hypothetical protein TIGR00150; Identified by similarity to GB:CAE20312.1; match to protein family HMM PF02367; match to protein family HMM TIGR00150. | tRNA delta(2)-isopentenylpyrophosphate transferase; Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A); Belongs to the IPP transferase family. | 0.485 |
| sync_0107 | nnrD | sync_0107 | sync_0760 | Conserved hypothetical protein TIGR00150; Identified by similarity to GB:CAE20312.1; match to protein family HMM PF02367; match to protein family HMM TIGR00150. | Carbohydrate kinase family protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. In the C-terminal section; belongs to the NnrD/CARKD family. | 0.700 |
| sync_0107 | sync_0541 | sync_0107 | sync_0541 | Conserved hypothetical protein TIGR00150; Identified by similarity to GB:CAE20312.1; match to protein family HMM PF02367; match to protein family HMM TIGR00150. | yrdC domain, putative; Identified by match to protein family HMM PF01300; Belongs to the SUA5 family. | 0.681 |
| sync_0107 | sync_2603 | sync_0107 | sync_2603 | Conserved hypothetical protein TIGR00150; Identified by similarity to GB:CAE20312.1; match to protein family HMM PF02367; match to protein family HMM TIGR00150. | Identified by match to protein family HMM PF00814. | 0.996 |
