| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| metK | mscL | sync_0529 | sync_0202 | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | Large conductance mechanosensitive channel protein; Identified by match to protein family HMM PF01741; match to protein family HMM TIGR00220. | 0.664 |
| metK | polA | sync_0529 | sync_0928 | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.545 |
| metK | ribH | sync_0529 | sync_0081 | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.848 |
| metK | sync_2281 | sync_0529 | sync_2281 | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | Large-conductive mechanosensitive channel. | 0.664 |
| mscL | metK | sync_0202 | sync_0529 | Large conductance mechanosensitive channel protein; Identified by match to protein family HMM PF01741; match to protein family HMM TIGR00220. | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.664 |
| mscL | napA | sync_0202 | sync_1045 | Large conductance mechanosensitive channel protein; Identified by match to protein family HMM PF01741; match to protein family HMM TIGR00220. | Transporter, monovalent cation:proton antiporter-2 (CPA2) family protein; Identified by match to protein family HMM PF00582; match to protein family HMM PF00999. | 0.402 |
| mscL | polA | sync_0202 | sync_0928 | Large conductance mechanosensitive channel protein; Identified by match to protein family HMM PF01741; match to protein family HMM TIGR00220. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.414 |
| mscL | ribH | sync_0202 | sync_0081 | Large conductance mechanosensitive channel protein; Identified by match to protein family HMM PF01741; match to protein family HMM TIGR00220. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.700 |
| mscL | sync_0203 | sync_0202 | sync_0203 | Large conductance mechanosensitive channel protein; Identified by match to protein family HMM PF01741; match to protein family HMM TIGR00220. | Conserved hypothetical protein; Identified by similarity to GB:CAE22122.1. | 0.527 |
| mscL | sync_0204 | sync_0202 | sync_0204 | Large conductance mechanosensitive channel protein; Identified by match to protein family HMM PF01741; match to protein family HMM TIGR00220. | Conserved hypothetical protein; Identified by similarity to GB:CAE22121.1. | 0.446 |
| mscL | sync_2281 | sync_0202 | sync_2281 | Large conductance mechanosensitive channel protein; Identified by match to protein family HMM PF01741; match to protein family HMM TIGR00220. | Large-conductive mechanosensitive channel. | 0.769 |
| napA | mscL | sync_1045 | sync_0202 | Transporter, monovalent cation:proton antiporter-2 (CPA2) family protein; Identified by match to protein family HMM PF00582; match to protein family HMM PF00999. | Large conductance mechanosensitive channel protein; Identified by match to protein family HMM PF01741; match to protein family HMM TIGR00220. | 0.402 |
| napA | sync_2281 | sync_1045 | sync_2281 | Transporter, monovalent cation:proton antiporter-2 (CPA2) family protein; Identified by match to protein family HMM PF00582; match to protein family HMM PF00999. | Large-conductive mechanosensitive channel. | 0.402 |
| polA | metK | sync_0928 | sync_0529 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.545 |
| polA | mscL | sync_0928 | sync_0202 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | Large conductance mechanosensitive channel protein; Identified by match to protein family HMM PF01741; match to protein family HMM TIGR00220. | 0.414 |
| polA | sync_2281 | sync_0928 | sync_2281 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | Large-conductive mechanosensitive channel. | 0.414 |
| ribH | metK | sync_0081 | sync_0529 | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | S-adenosylmethionine synthetase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.848 |
| ribH | mscL | sync_0081 | sync_0202 | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | Large conductance mechanosensitive channel protein; Identified by match to protein family HMM PF01741; match to protein family HMM TIGR00220. | 0.700 |
| ribH | sync_2281 | sync_0081 | sync_2281 | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | Large-conductive mechanosensitive channel. | 0.700 |
| sync_0203 | mscL | sync_0203 | sync_0202 | Conserved hypothetical protein; Identified by similarity to GB:CAE22122.1. | Large conductance mechanosensitive channel protein; Identified by match to protein family HMM PF01741; match to protein family HMM TIGR00220. | 0.527 |