icd protein (Synechococcus sp. CC9311) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

icd

Isocitrate dehydrogenase, NADP-dependent; Identified by match to protein family HMM PF00180; match to protein family HMM TIGR00183. (482 aa)

Predicted Functional Partners:

acnB

0.987

citZ

0.980

gcvP

0.908

sync_1835

0.844

purB

0.842

sync_0156

0.831

aspC

0.822

argH

0.817

nadB

0.817

leuB

0.813

Your Current Organism:

Synechococcus sp. CC9311

NCBI taxonomy Id: 64471
Other names: S. sp. CC9311

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
acnB	citZ	sync_2910	sync_2626	Aconitate hydratase 2; Identified by match to protein family HMM PF00330; match to protein family HMM PF06434; match to protein family HMM TIGR00117; Belongs to the aconitase/IPM isomerase family.	Citrate synthase; Identified by match to protein family HMM PF00285; match to protein family HMM TIGR01800; Belongs to the citrate synthase family.	0.960
acnB	icd	sync_2910	sync_0214	Aconitate hydratase 2; Identified by match to protein family HMM PF00330; match to protein family HMM PF06434; match to protein family HMM TIGR00117; Belongs to the aconitase/IPM isomerase family.	Isocitrate dehydrogenase, NADP-dependent; Identified by match to protein family HMM PF00180; match to protein family HMM TIGR00183.	0.987
argH	citZ	sync_0013	sync_2626	Argininosuccinate lyase; Identified by match to protein family HMM PF00206; match to protein family HMM TIGR00838.	Citrate synthase; Identified by match to protein family HMM PF00285; match to protein family HMM TIGR01800; Belongs to the citrate synthase family.	0.822
argH	gcvP	sync_0013	sync_2788	Argininosuccinate lyase; Identified by match to protein family HMM PF00206; match to protein family HMM TIGR00838.	Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.	0.584
argH	icd	sync_0013	sync_0214	Argininosuccinate lyase; Identified by match to protein family HMM PF00206; match to protein family HMM TIGR00838.	Isocitrate dehydrogenase, NADP-dependent; Identified by match to protein family HMM PF00180; match to protein family HMM TIGR00183.	0.817
argH	purB	sync_0013	sync_2334	Argininosuccinate lyase; Identified by match to protein family HMM PF00206; match to protein family HMM TIGR00838.	Adenylosuccinate lyase; Identified by match to protein family HMM PF00206; match to protein family HMM TIGR00928; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.	0.917
argH	sync_0156	sync_0013	sync_0156	Argininosuccinate lyase; Identified by match to protein family HMM PF00206; match to protein family HMM TIGR00838.	Polyketide synthase, putative; Identified by match to protein family HMM PF00106; match to protein family HMM PF00107; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02801; match to protein family HMM PF07993; match to protein family HMM TIGR01746.	0.575
aspC	citZ	sync_1671	sync_2626	Aspartate aminotransferase; Identified by similarity to SP:Q56232; match to protein family HMM PF00155.	Citrate synthase; Identified by match to protein family HMM PF00285; match to protein family HMM TIGR01800; Belongs to the citrate synthase family.	0.826
aspC	icd	sync_1671	sync_0214	Aspartate aminotransferase; Identified by similarity to SP:Q56232; match to protein family HMM PF00155.	Isocitrate dehydrogenase, NADP-dependent; Identified by match to protein family HMM PF00180; match to protein family HMM TIGR00183.	0.822
aspC	nadB	sync_1671	sync_2546	Aspartate aminotransferase; Identified by similarity to SP:Q56232; match to protein family HMM PF00155.	L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate.	0.818
aspC	sync_0156	sync_1671	sync_0156	Aspartate aminotransferase; Identified by similarity to SP:Q56232; match to protein family HMM PF00155.	Polyketide synthase, putative; Identified by match to protein family HMM PF00106; match to protein family HMM PF00107; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02801; match to protein family HMM PF07993; match to protein family HMM TIGR01746.	0.628
citZ	acnB	sync_2626	sync_2910	Citrate synthase; Identified by match to protein family HMM PF00285; match to protein family HMM TIGR01800; Belongs to the citrate synthase family.	Aconitate hydratase 2; Identified by match to protein family HMM PF00330; match to protein family HMM PF06434; match to protein family HMM TIGR00117; Belongs to the aconitase/IPM isomerase family.	0.960
citZ	argH	sync_2626	sync_0013	Citrate synthase; Identified by match to protein family HMM PF00285; match to protein family HMM TIGR01800; Belongs to the citrate synthase family.	Argininosuccinate lyase; Identified by match to protein family HMM PF00206; match to protein family HMM TIGR00838.	0.822
citZ	aspC	sync_2626	sync_1671	Citrate synthase; Identified by match to protein family HMM PF00285; match to protein family HMM TIGR01800; Belongs to the citrate synthase family.	Aspartate aminotransferase; Identified by similarity to SP:Q56232; match to protein family HMM PF00155.	0.826
citZ	gcvP	sync_2626	sync_2788	Citrate synthase; Identified by match to protein family HMM PF00285; match to protein family HMM TIGR01800; Belongs to the citrate synthase family.	Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.	0.486
citZ	icd	sync_2626	sync_0214	Citrate synthase; Identified by match to protein family HMM PF00285; match to protein family HMM TIGR01800; Belongs to the citrate synthase family.	Isocitrate dehydrogenase, NADP-dependent; Identified by match to protein family HMM PF00180; match to protein family HMM TIGR00183.	0.980
citZ	leuB	sync_2626	sync_1712	Citrate synthase; Identified by match to protein family HMM PF00285; match to protein family HMM TIGR01800; Belongs to the citrate synthase family.	3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.	0.863
citZ	nadB	sync_2626	sync_2546	Citrate synthase; Identified by match to protein family HMM PF00285; match to protein family HMM TIGR01800; Belongs to the citrate synthase family.	L-aspartate oxidase; Catalyzes the oxidation of L-aspartate to iminoaspartate.	0.858
citZ	purB	sync_2626	sync_2334	Citrate synthase; Identified by match to protein family HMM PF00285; match to protein family HMM TIGR01800; Belongs to the citrate synthase family.	Adenylosuccinate lyase; Identified by match to protein family HMM PF00206; match to protein family HMM TIGR00928; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.	0.800
citZ	sync_0156	sync_2626	sync_0156	Citrate synthase; Identified by match to protein family HMM PF00285; match to protein family HMM TIGR01800; Belongs to the citrate synthase family.	Polyketide synthase, putative; Identified by match to protein family HMM PF00106; match to protein family HMM PF00107; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02801; match to protein family HMM PF07993; match to protein family HMM TIGR01746.	0.715