| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| aroE | polA | sync_2924 | sync_0928 | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.466 |
| aroE | sync_0541 | sync_2924 | sync_0541 | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | yrdC domain, putative; Identified by match to protein family HMM PF01300; Belongs to the SUA5 family. | 0.450 |
| gcp | polA | sync_2156 | sync_0928 | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.579 |
| gcp | sync_0107 | sync_2156 | sync_0107 | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | Conserved hypothetical protein TIGR00150; Identified by similarity to GB:CAE20312.1; match to protein family HMM PF02367; match to protein family HMM TIGR00150. | 0.987 |
| gcp | sync_0541 | sync_2156 | sync_0541 | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | yrdC domain, putative; Identified by match to protein family HMM PF01300; Belongs to the SUA5 family. | 0.744 |
| gcp | sync_2603 | sync_2156 | sync_2603 | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | Identified by match to protein family HMM PF00814. | 0.996 |
| polA | aroE | sync_0928 | sync_2924 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.466 |
| polA | gcp | sync_0928 | sync_2156 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.579 |
| polA | sync_0107 | sync_0928 | sync_0107 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | Conserved hypothetical protein TIGR00150; Identified by similarity to GB:CAE20312.1; match to protein family HMM PF02367; match to protein family HMM TIGR00150. | 0.403 |
| polA | sync_0541 | sync_0928 | sync_0541 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | yrdC domain, putative; Identified by match to protein family HMM PF01300; Belongs to the SUA5 family. | 0.465 |
| polA | sync_1174 | sync_0928 | sync_1174 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | RecF/RecN/SMC N terminal domain protein. | 0.937 |
| prmC | sync_0537 | sync_0540 | sync_0537 | Methyltransferase, HemK family protein; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily. | Identified by match to protein family HMM PF00582. | 0.488 |
| prmC | sync_0538 | sync_0540 | sync_0538 | Methyltransferase, HemK family protein; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily. | Predicted thioesterase; Identified by match to protein family HMM PF03061. | 0.689 |
| prmC | sync_0539 | sync_0540 | sync_0539 | Methyltransferase, HemK family protein; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily. | Putative DNA protecting protein DprA; Identified by match to protein family HMM PF02481. | 0.779 |
| prmC | sync_0541 | sync_0540 | sync_0541 | Methyltransferase, HemK family protein; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily. | yrdC domain, putative; Identified by match to protein family HMM PF01300; Belongs to the SUA5 family. | 0.870 |
| sync_0107 | gcp | sync_0107 | sync_2156 | Conserved hypothetical protein TIGR00150; Identified by similarity to GB:CAE20312.1; match to protein family HMM PF02367; match to protein family HMM TIGR00150. | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.987 |
| sync_0107 | polA | sync_0107 | sync_0928 | Conserved hypothetical protein TIGR00150; Identified by similarity to GB:CAE20312.1; match to protein family HMM PF02367; match to protein family HMM TIGR00150. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.403 |
| sync_0107 | sync_0541 | sync_0107 | sync_0541 | Conserved hypothetical protein TIGR00150; Identified by similarity to GB:CAE20312.1; match to protein family HMM PF02367; match to protein family HMM TIGR00150. | yrdC domain, putative; Identified by match to protein family HMM PF01300; Belongs to the SUA5 family. | 0.665 |
| sync_0107 | sync_2603 | sync_0107 | sync_2603 | Conserved hypothetical protein TIGR00150; Identified by similarity to GB:CAE20312.1; match to protein family HMM PF02367; match to protein family HMM TIGR00150. | Identified by match to protein family HMM PF00814. | 0.994 |
| sync_0537 | prmC | sync_0537 | sync_0540 | Identified by match to protein family HMM PF00582. | Methyltransferase, HemK family protein; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily. | 0.488 |