| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| aroE | polA | sync_2924 | sync_0928 | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.442 |
| aroE | sync_0541 | sync_2924 | sync_0541 | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | yrdC domain, putative; Identified by match to protein family HMM PF01300; Belongs to the SUA5 family. | 0.460 |
| gcp | polA | sync_2156 | sync_0928 | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.464 |
| gcp | sync_0107 | sync_2156 | sync_0107 | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | Conserved hypothetical protein TIGR00150; Identified by similarity to GB:CAE20312.1; match to protein family HMM PF02367; match to protein family HMM TIGR00150. | 0.987 |
| gcp | sync_0541 | sync_2156 | sync_0541 | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | yrdC domain, putative; Identified by match to protein family HMM PF01300; Belongs to the SUA5 family. | 0.757 |
| gcp | sync_2603 | sync_2156 | sync_2603 | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | Identified by match to protein family HMM PF00814. | 0.993 |
| polA | aroE | sync_0928 | sync_2924 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.442 |
| polA | gcp | sync_0928 | sync_2156 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.464 |
| polA | sync_0107 | sync_0928 | sync_0107 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | Conserved hypothetical protein TIGR00150; Identified by similarity to GB:CAE20312.1; match to protein family HMM PF02367; match to protein family HMM TIGR00150. | 0.428 |
| polA | sync_0541 | sync_0928 | sync_0541 | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | yrdC domain, putative; Identified by match to protein family HMM PF01300; Belongs to the SUA5 family. | 0.478 |
| prmC | sync_0537 | sync_0540 | sync_0537 | Methyltransferase, HemK family protein; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily. | Identified by match to protein family HMM PF00582. | 0.488 |
| prmC | sync_0538 | sync_0540 | sync_0538 | Methyltransferase, HemK family protein; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily. | Predicted thioesterase; Identified by match to protein family HMM PF03061. | 0.724 |
| prmC | sync_0539 | sync_0540 | sync_0539 | Methyltransferase, HemK family protein; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily. | Putative DNA protecting protein DprA; Identified by match to protein family HMM PF02481. | 0.819 |
| prmC | sync_0541 | sync_0540 | sync_0541 | Methyltransferase, HemK family protein; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily. | yrdC domain, putative; Identified by match to protein family HMM PF01300; Belongs to the SUA5 family. | 0.864 |
| sync_0107 | gcp | sync_0107 | sync_2156 | Conserved hypothetical protein TIGR00150; Identified by similarity to GB:CAE20312.1; match to protein family HMM PF02367; match to protein family HMM TIGR00150. | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.987 |
| sync_0107 | polA | sync_0107 | sync_0928 | Conserved hypothetical protein TIGR00150; Identified by similarity to GB:CAE20312.1; match to protein family HMM PF02367; match to protein family HMM TIGR00150. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.428 |
| sync_0107 | sync_0541 | sync_0107 | sync_0541 | Conserved hypothetical protein TIGR00150; Identified by similarity to GB:CAE20312.1; match to protein family HMM PF02367; match to protein family HMM TIGR00150. | yrdC domain, putative; Identified by match to protein family HMM PF01300; Belongs to the SUA5 family. | 0.681 |
| sync_0107 | sync_2603 | sync_0107 | sync_2603 | Conserved hypothetical protein TIGR00150; Identified by similarity to GB:CAE20312.1; match to protein family HMM PF02367; match to protein family HMM TIGR00150. | Identified by match to protein family HMM PF00814. | 0.996 |
| sync_0107 | ybeY | sync_0107 | sync_2661 | Conserved hypothetical protein TIGR00150; Identified by similarity to GB:CAE20312.1; match to protein family HMM PF02367; match to protein family HMM TIGR00150. | Hypothetical UPF0054 protein; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. | 0.433 |
| sync_0537 | prmC | sync_0537 | sync_0540 | Identified by match to protein family HMM PF00582. | Methyltransferase, HemK family protein; Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif; Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily. | 0.488 |