STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sync_0566NAD-dependent aldehyde dehydrogenase; Identified by match to protein family HMM PF00171; Belongs to the aldehyde dehydrogenase family. (466 aa)    
Predicted Functional Partners:
acsA
acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 0.943
sync_1463
D-isomer specific 2-hydroxyacid dehydrogenase family protein; Identified by match to protein family HMM PF00107; match to protein family HMM TIGR02818.
  
 0.927
sync_2080
Identified by match to protein family HMM PF00171; Belongs to the aldehyde dehydrogenase family.
  
  
 
0.927
panC/cmk
Pantoate--beta-alanine ligase/cytidylate kinase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. In the C-terminal section; belongs to the cytidylate kinase family. Type 1 subfamily.
    
 0.923
sync_0822
Alcohol dehydrogenase; Identified by match to protein family HMM PF00248.
   
 0.917
sync_1491
Indolepyruvate decarboxylase; Identified by match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776.
   
 0.914
sync_0455
Glutamate decarboxylase; Identified by match to protein family HMM PF00282; match to protein family HMM TIGR01788; Belongs to the group II decarboxylase family.
   
 0.912
acyP
Acylphosphatase; Identified by match to protein family HMM PF00708.
    
 0.906
sync_1318
Phosphoribulokinase/uridine kinase family enzyme.
     
  0.900
sync_0105
Putative glutamine synthetase; Identified by match to protein family HMM PF00120; Belongs to the glutamine synthetase family.
  
 
 0.814
Your Current Organism:
Synechococcus sp. CC9311
NCBI taxonomy Id: 64471
Other names: S. sp. CC9311
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.