| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| murD | murI | sync_2260 | sync_1550 | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.975 |
| murD | purQ | sync_2260 | sync_1701 | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.900 |
| murD | sync_0737 | sync_2260 | sync_0737 | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | Uncharacterized conserved protein; Identified by match to protein family HMM PF07755. | 0.900 |
| murI | murD | sync_1550 | sync_2260 | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.975 |
| murI | purQ | sync_1550 | sync_1701 | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.900 |
| murI | sync_0737 | sync_1550 | sync_0737 | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | Uncharacterized conserved protein; Identified by match to protein family HMM PF07755. | 0.900 |
| purQ | murD | sync_1701 | sync_2260 | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.900 |
| purQ | murI | sync_1701 | sync_1550 | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.900 |
| purQ | sync_0737 | sync_1701 | sync_0737 | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | Uncharacterized conserved protein; Identified by match to protein family HMM PF07755. | 0.900 |
| sync_0736 | sync_0737 | sync_0736 | sync_0737 | Muconate cycloisomerase; Identified by match to protein family HMM PF01188; match to protein family HMM PF02746; Belongs to the mandelate racemase/muconate lactonizing enzyme family. | Uncharacterized conserved protein; Identified by match to protein family HMM PF07755. | 0.883 |
| sync_0736 | sync_0739 | sync_0736 | sync_0739 | Muconate cycloisomerase; Identified by match to protein family HMM PF01188; match to protein family HMM PF02746; Belongs to the mandelate racemase/muconate lactonizing enzyme family. | Conserved hypothetical protein. | 0.511 |
| sync_0736 | sync_0740 | sync_0736 | sync_0740 | Muconate cycloisomerase; Identified by match to protein family HMM PF01188; match to protein family HMM PF02746; Belongs to the mandelate racemase/muconate lactonizing enzyme family. | Identified by match to protein family HMM PF07969. | 0.425 |
| sync_0736 | sync_0741 | sync_0736 | sync_0741 | Muconate cycloisomerase; Identified by match to protein family HMM PF01188; match to protein family HMM PF02746; Belongs to the mandelate racemase/muconate lactonizing enzyme family. | FAD linked oxidase, N-terminal; Identified by match to protein family HMM PF01565. | 0.421 |
| sync_0736 | sync_1335 | sync_0736 | sync_1335 | Muconate cycloisomerase; Identified by match to protein family HMM PF01188; match to protein family HMM PF02746; Belongs to the mandelate racemase/muconate lactonizing enzyme family. | Conserved hypothetical protein. | 0.480 |
| sync_0737 | murD | sync_0737 | sync_2260 | Uncharacterized conserved protein; Identified by match to protein family HMM PF07755. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.900 |
| sync_0737 | murI | sync_0737 | sync_1550 | Uncharacterized conserved protein; Identified by match to protein family HMM PF07755. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.900 |
| sync_0737 | purQ | sync_0737 | sync_1701 | Uncharacterized conserved protein; Identified by match to protein family HMM PF07755. | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.900 |
| sync_0737 | sync_0736 | sync_0737 | sync_0736 | Uncharacterized conserved protein; Identified by match to protein family HMM PF07755. | Muconate cycloisomerase; Identified by match to protein family HMM PF01188; match to protein family HMM PF02746; Belongs to the mandelate racemase/muconate lactonizing enzyme family. | 0.883 |
| sync_0737 | sync_0739 | sync_0737 | sync_0739 | Uncharacterized conserved protein; Identified by match to protein family HMM PF07755. | Conserved hypothetical protein. | 0.787 |
| sync_0737 | sync_0740 | sync_0737 | sync_0740 | Uncharacterized conserved protein; Identified by match to protein family HMM PF07755. | Identified by match to protein family HMM PF07969. | 0.719 |