hom protein (Synechococcus sp. CC9311) - STRING interaction network

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[Homology]

Score

hom

Homoserine dehydrogenase; Identified by match to protein family HMM PF00742; match to protein family HMM PF01842; match to protein family HMM PF03447. (438 aa)

Predicted Functional Partners:

thrB

0.994

asd

0.969

dapA

0.959

thrC

0.950

metH

0.944

metA

0.939

ilvE

0.884

sync_0622

0.868

metB

0.868

sync_0075

0.836

Your Current Organism:

Synechococcus sp. CC9311

NCBI taxonomy Id: 64471
Other names: S. sp. CC9311

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
asd	dapA	sync_0067	sync_0068	Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.	Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).	0.995
asd	hom	sync_0067	sync_0941	Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.	Homoserine dehydrogenase; Identified by match to protein family HMM PF00742; match to protein family HMM PF01842; match to protein family HMM PF03447.	0.969
asd	metH	sync_0067	sync_1353	Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.	Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	0.616
asd	sync_0075	sync_0067	sync_0075	Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.	Asparate kinase, monofunctional class; Identified by similarity to SP:P08495; match to protein family HMM PF00696; match to protein family HMM PF01842; match to protein family HMM TIGR00656; match to protein family HMM TIGR00657.	0.989
asd	thrB	sync_0067	sync_1869	Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.	Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.	0.647
asd	thrC	sync_0067	sync_2943	Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.	Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine.	0.581
dapA	asd	sync_0068	sync_0067	Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).	Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.	0.995
dapA	hom	sync_0068	sync_0941	Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).	Homoserine dehydrogenase; Identified by match to protein family HMM PF00742; match to protein family HMM PF01842; match to protein family HMM PF03447.	0.959
dapA	sync_0075	sync_0068	sync_0075	Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).	Asparate kinase, monofunctional class; Identified by similarity to SP:P08495; match to protein family HMM PF00696; match to protein family HMM PF01842; match to protein family HMM TIGR00656; match to protein family HMM TIGR00657.	0.769
hom	asd	sync_0941	sync_0067	Homoserine dehydrogenase; Identified by match to protein family HMM PF00742; match to protein family HMM PF01842; match to protein family HMM PF03447.	Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family.	0.969
hom	dapA	sync_0941	sync_0068	Homoserine dehydrogenase; Identified by match to protein family HMM PF00742; match to protein family HMM PF01842; match to protein family HMM PF03447.	Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).	0.959
hom	ilvE	sync_0941	sync_1354	Homoserine dehydrogenase; Identified by match to protein family HMM PF00742; match to protein family HMM PF01842; match to protein family HMM PF03447.	Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.	0.884
hom	metA	sync_0941	sync_1181	Homoserine dehydrogenase; Identified by match to protein family HMM PF00742; match to protein family HMM PF01842; match to protein family HMM PF03447.	Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family.	0.939
hom	metB	sync_0941	sync_0623	Homoserine dehydrogenase; Identified by match to protein family HMM PF00742; match to protein family HMM PF01842; match to protein family HMM PF03447.	Cystathionine beta-lyase/cystathionine gamma-synthase; Identified by match to protein family HMM PF01053.	0.868
hom	metH	sync_0941	sync_1353	Homoserine dehydrogenase; Identified by match to protein family HMM PF00742; match to protein family HMM PF01842; match to protein family HMM PF03447.	Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	0.944
hom	sync_0075	sync_0941	sync_0075	Homoserine dehydrogenase; Identified by match to protein family HMM PF00742; match to protein family HMM PF01842; match to protein family HMM PF03447.	Asparate kinase, monofunctional class; Identified by similarity to SP:P08495; match to protein family HMM PF00696; match to protein family HMM PF01842; match to protein family HMM TIGR00656; match to protein family HMM TIGR00657.	0.836
hom	sync_0622	sync_0941	sync_0622	Homoserine dehydrogenase; Identified by match to protein family HMM PF00742; match to protein family HMM PF01842; match to protein family HMM PF03447.	Possible cystathionine gamma-synthase; Identified by match to protein family HMM PF01053.	0.868
hom	thrB	sync_0941	sync_1869	Homoserine dehydrogenase; Identified by match to protein family HMM PF00742; match to protein family HMM PF01842; match to protein family HMM PF03447.	Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.	0.994
hom	thrC	sync_0941	sync_2943	Homoserine dehydrogenase; Identified by match to protein family HMM PF00742; match to protein family HMM PF01842; match to protein family HMM PF03447.	Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine.	0.950
ilvE	hom	sync_1354	sync_0941	Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.	Homoserine dehydrogenase; Identified by match to protein family HMM PF00742; match to protein family HMM PF01842; match to protein family HMM PF03447.	0.884