| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| acsA | acyP | sync_1553 | sync_0999 | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Acylphosphatase; Identified by match to protein family HMM PF00708. | 0.904 |
| acsA | pyk | sync_1553 | sync_1415 | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Pyruvate kinase; Identified by match to protein family HMM PF00224; match to protein family HMM PF00391; match to protein family HMM PF02887; match to protein family HMM TIGR01064; Belongs to the pyruvate kinase family. | 0.599 |
| acsA | sync_0566 | sync_1553 | sync_0566 | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | NAD-dependent aldehyde dehydrogenase; Identified by match to protein family HMM PF00171; Belongs to the aldehyde dehydrogenase family. | 0.936 |
| acsA | sync_2080 | sync_1553 | sync_2080 | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | Identified by match to protein family HMM PF00171; Belongs to the aldehyde dehydrogenase family. | 0.915 |
| acyP | acsA | sync_0999 | sync_1553 | Acylphosphatase; Identified by match to protein family HMM PF00708. | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.904 |
| acyP | cobB | sync_0999 | sync_1000 | Acylphosphatase; Identified by match to protein family HMM PF00708. | Cobyrinic acid a,c-diamide synthase; Identified by match to protein family HMM PF01656; match to protein family HMM PF07685; match to protein family HMM TIGR00379. | 0.704 |
| acyP | pyk | sync_0999 | sync_1415 | Acylphosphatase; Identified by match to protein family HMM PF00708. | Pyruvate kinase; Identified by match to protein family HMM PF00224; match to protein family HMM PF00391; match to protein family HMM PF02887; match to protein family HMM TIGR01064; Belongs to the pyruvate kinase family. | 0.412 |
| acyP | sync_0566 | sync_0999 | sync_0566 | Acylphosphatase; Identified by match to protein family HMM PF00708. | NAD-dependent aldehyde dehydrogenase; Identified by match to protein family HMM PF00171; Belongs to the aldehyde dehydrogenase family. | 0.905 |
| acyP | sync_0998 | sync_0999 | sync_0998 | Acylphosphatase; Identified by match to protein family HMM PF00708. | EntD; Identified by match to protein family HMM PF00300. | 0.507 |
| acyP | sync_1001 | sync_0999 | sync_1001 | Acylphosphatase; Identified by match to protein family HMM PF00708. | Possible glucose 6-phosphate dehydrogenase effector OpcA. | 0.666 |
| acyP | sync_1003 | sync_0999 | sync_1003 | Acylphosphatase; Identified by match to protein family HMM PF00708. | ferredoxin--NADP reductase; Identified by match to protein family HMM PF00175. | 0.411 |
| acyP | sync_2080 | sync_0999 | sync_2080 | Acylphosphatase; Identified by match to protein family HMM PF00708. | Identified by match to protein family HMM PF00171; Belongs to the aldehyde dehydrogenase family. | 0.905 |
| acyP | zwf | sync_0999 | sync_1002 | Acylphosphatase; Identified by match to protein family HMM PF00708. | Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. | 0.661 |
| cobB | acyP | sync_1000 | sync_0999 | Cobyrinic acid a,c-diamide synthase; Identified by match to protein family HMM PF01656; match to protein family HMM PF07685; match to protein family HMM TIGR00379. | Acylphosphatase; Identified by match to protein family HMM PF00708. | 0.704 |
| cobB | sync_0998 | sync_1000 | sync_0998 | Cobyrinic acid a,c-diamide synthase; Identified by match to protein family HMM PF01656; match to protein family HMM PF07685; match to protein family HMM TIGR00379. | EntD; Identified by match to protein family HMM PF00300. | 0.512 |
| cobB | sync_1001 | sync_1000 | sync_1001 | Cobyrinic acid a,c-diamide synthase; Identified by match to protein family HMM PF01656; match to protein family HMM PF07685; match to protein family HMM TIGR00379. | Possible glucose 6-phosphate dehydrogenase effector OpcA. | 0.782 |
| cobB | sync_1003 | sync_1000 | sync_1003 | Cobyrinic acid a,c-diamide synthase; Identified by match to protein family HMM PF01656; match to protein family HMM PF07685; match to protein family HMM TIGR00379. | ferredoxin--NADP reductase; Identified by match to protein family HMM PF00175. | 0.545 |
| cobB | zwf | sync_1000 | sync_1002 | Cobyrinic acid a,c-diamide synthase; Identified by match to protein family HMM PF01656; match to protein family HMM PF07685; match to protein family HMM TIGR00379. | Glucose-6-phosphate 1-dehydrogenase; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone. | 0.782 |
| pyk | acsA | sync_1415 | sync_1553 | Pyruvate kinase; Identified by match to protein family HMM PF00224; match to protein family HMM PF00391; match to protein family HMM PF02887; match to protein family HMM TIGR01064; Belongs to the pyruvate kinase family. | acetate--CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.599 |
| pyk | acyP | sync_1415 | sync_0999 | Pyruvate kinase; Identified by match to protein family HMM PF00224; match to protein family HMM PF00391; match to protein family HMM PF02887; match to protein family HMM TIGR01064; Belongs to the pyruvate kinase family. | Acylphosphatase; Identified by match to protein family HMM PF00708. | 0.412 |