STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sasAAdaptive-response sensory histidine kinase SasA; May be involved in signal transduction. Participates in the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria, via its interaction with KaiC. Required for robustness of the circadian rhythm of gene expression and is involved in clock outputs. (383 aa)    
Predicted Functional Partners:
kaiC
Circadian clock protein KaiC; Core component of the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria. Binds to DNA. The KaiABC complex may act as a promoter-nonspecific transcription regulator that represses transcription, possibly by acting on the state of chromosome compaction; Belongs to the KaiC family.
    
 
 0.996
sync_2591
DNA-binding response regulator RpaA; Identified by similarity to GB:AAD30120.2; match to protein family HMM PF00072; match to protein family HMM PF00486.
 
 0.981
sync_1079
Sensory box histidine kinase/response regulator; Identified by match to protein family HMM PF00072; match to protein family HMM PF00512; match to protein family HMM PF02518.
 
0.838
sync_0115
Two-component response regulator; Identified by match to protein family HMM PF00072; match to protein family HMM PF00486.
 
 
 0.821
sync_2597
DNA-binding response regulator; Identified by match to protein family HMM PF00072; match to protein family HMM PF00486.
 
 
 0.816
sync_2642
DNA-binding response regulator; Identified by match to protein family HMM PF00072; match to protein family HMM PF00196.
 
 
 
 0.805
sync_2111
DNA-binding response regulator; Identified by match to protein family HMM PF00072; match to protein family HMM PF00486.
  
 
 0.798
sync_0669
Two-component response regulator; Identified by match to protein family HMM PF00072; match to protein family HMM PF00486.
  
 
 0.791
sync_0707
DNA-binding response regulator; Identified by match to protein family HMM PF00072; match to protein family HMM PF00486.
 
 
 0.791
sync_1134
Response regulator receiver domain; Identified by match to protein family HMM PF00072.
 
 
 
 0.785
Your Current Organism:
Synechococcus sp. CC9311
NCBI taxonomy Id: 64471
Other names: S. sp. CC9311
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