| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| bioB | dacA | sync_1032 | sync_1030 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Conserved hypothetical protein TIGR00159; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. | 0.649 |
| bioB | lysA | sync_1032 | sync_1029 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.646 |
| bioB | rimI | sync_1032 | sync_1028 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Ribosomal-protein-alanine acetyltransferase; Identified by match to protein family HMM PF00583. | 0.492 |
| bioB | sync_0156 | sync_1032 | sync_0156 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Polyketide synthase, putative; Identified by match to protein family HMM PF00106; match to protein family HMM PF00107; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02801; match to protein family HMM PF07993; match to protein family HMM TIGR01746. | 0.892 |
| bioB | sync_1034 | sync_1032 | sync_1034 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Rhodanese domain protein; Identified by match to protein family HMM PF00581; Belongs to the UPF0176 family. | 0.592 |
| bioB | uppS | sync_1032 | sync_1031 | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | Undecaprenyl diphosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. | 0.649 |
| dacA | bioB | sync_1030 | sync_1032 | Conserved hypothetical protein TIGR00159; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.649 |
| dacA | lysA | sync_1030 | sync_1029 | Conserved hypothetical protein TIGR00159; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.830 |
| dacA | rimI | sync_1030 | sync_1028 | Conserved hypothetical protein TIGR00159; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. | Ribosomal-protein-alanine acetyltransferase; Identified by match to protein family HMM PF00583. | 0.588 |
| dacA | sync_1026 | sync_1030 | sync_1026 | Conserved hypothetical protein TIGR00159; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. | Glycerol dehydrogenase family enzyme; Identified by match to protein family HMM PF00465. | 0.414 |
| dacA | sync_1027 | sync_1030 | sync_1027 | Conserved hypothetical protein TIGR00159; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. | Putative Clp protease, ATP-binding subunit ClpC; Identified by match to protein family HMM PF00004; match to protein family HMM PF02151; match to protein family HMM PF02861; match to protein family HMM PF07724; Belongs to the ClpA/ClpB family. | 0.428 |
| dacA | sync_1034 | sync_1030 | sync_1034 | Conserved hypothetical protein TIGR00159; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. | Rhodanese domain protein; Identified by match to protein family HMM PF00581; Belongs to the UPF0176 family. | 0.497 |
| dacA | uppS | sync_1030 | sync_1031 | Conserved hypothetical protein TIGR00159; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. | Undecaprenyl diphosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. | 0.883 |
| guaA | lysA | sync_0047 | sync_1029 | GMP synthase, glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP. | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | 0.672 |
| guaA | rimI | sync_0047 | sync_1028 | GMP synthase, glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP. | Ribosomal-protein-alanine acetyltransferase; Identified by match to protein family HMM PF00583. | 0.453 |
| guaA | sync_0156 | sync_0047 | sync_0156 | GMP synthase, glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP. | Polyketide synthase, putative; Identified by match to protein family HMM PF00106; match to protein family HMM PF00107; match to protein family HMM PF00109; match to protein family HMM PF00550; match to protein family HMM PF01073; match to protein family HMM PF01370; match to protein family HMM PF02801; match to protein family HMM PF07993; match to protein family HMM TIGR01746. | 0.738 |
| guaA | uppS | sync_0047 | sync_1031 | GMP synthase, glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP. | Undecaprenyl diphosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. | 0.531 |
| lysA | bioB | sync_1029 | sync_1032 | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.646 |
| lysA | dacA | sync_1029 | sync_1030 | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | Conserved hypothetical protein TIGR00159; Catalyzes the condensation of 2 ATP molecules into cyclic di- AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria. | 0.830 |
| lysA | guaA | sync_1029 | sync_0047 | Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. | GMP synthase, glutamine-hydrolyzing; Catalyzes the synthesis of GMP from XMP. | 0.672 |