STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sync_1145Two-component response regulator; Identified by match to protein family HMM PF00072; match to protein family HMM PF00486. (254 aa)    
Predicted Functional Partners:
sync_0573
Two-component hybrid sensor and regulator alr4878, putative; Identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518.
  
 
 0.875
sync_0286
Two-component sensor histidine kinase; Identified by match to protein family HMM PF00512; match to protein family HMM PF02518.
  
 
 0.782
sasA
Adaptive-response sensory histidine kinase SasA; May be involved in signal transduction. Participates in the KaiABC clock protein complex, which constitutes the main circadian regulator in cyanobacteria, via its interaction with KaiC. Required for robustness of the circadian rhythm of gene expression and is involved in clock outputs.
  
 
 0.780
sync_0807
Possible two-component response regulator; May be pseudogene; identified by match to protein family HMM PF00486.
  
     0.771
sync_1144
Hypothetical protein; Identified by Glimmer2; putative.
       0.762
sync_0263
Two component sensor histidine kinase, putative; Identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518.
  
 
 0.756
sync_1133
Histidine protein kinase; Identified by match to protein family HMM PF00512; match to protein family HMM PF02518.
  
 
 0.751
envZ
Two-component sensor histidine kinase; Identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518.
  
 
 0.750
sync_0706
Sensor histidine kinase; Identified by match to protein family HMM PF00512; match to protein family HMM PF00672; match to protein family HMM PF02518.
  
 
 0.747
sync_1134
Response regulator receiver domain; Identified by match to protein family HMM PF00072.
  
 
 0.747
Your Current Organism:
Synechococcus sp. CC9311
NCBI taxonomy Id: 64471
Other names: S. sp. CC9311
Server load: low (36%) [HD]