| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| dnaA | recF | sync_1933 | sync_0457 | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | DNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family. | 0.748 |
| dnaA | sync_1209 | sync_1933 | sync_1209 | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | S4 domain protein; Identified by match to protein family HMM PF01479. | 0.434 |
| folP | sync_1207 | sync_1211 | sync_1207 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Conserved hypothetical protein. | 0.511 |
| folP | sync_1208 | sync_1211 | sync_1208 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | ABC transporter, permease/ATP-binding protein; Identified by match to protein family HMM PF00005; match to protein family HMM PF00664. | 0.576 |
| folP | sync_1209 | sync_1211 | sync_1209 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | S4 domain protein; Identified by match to protein family HMM PF01479. | 0.719 |
| folP | sync_1212 | sync_1211 | sync_1212 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Uncharacterized conserved protein; Identified by match to protein family HMM PF04134. | 0.686 |
| folP | tpiA | sync_1211 | sync_1210 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.839 |
| recF | dnaA | sync_0457 | sync_1933 | DNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family. | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | 0.748 |
| recF | sync_1209 | sync_0457 | sync_1209 | DNA replication and repair protein RecF; The RecF protein is involved in DNA metabolism; it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP; Belongs to the RecF family. | S4 domain protein; Identified by match to protein family HMM PF01479. | 0.764 |
| sync_1207 | folP | sync_1207 | sync_1211 | Conserved hypothetical protein. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.511 |
| sync_1207 | sync_1208 | sync_1207 | sync_1208 | Conserved hypothetical protein. | ABC transporter, permease/ATP-binding protein; Identified by match to protein family HMM PF00005; match to protein family HMM PF00664. | 0.697 |
| sync_1207 | sync_1209 | sync_1207 | sync_1209 | Conserved hypothetical protein. | S4 domain protein; Identified by match to protein family HMM PF01479. | 0.559 |
| sync_1207 | tpiA | sync_1207 | sync_1210 | Conserved hypothetical protein. | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.511 |
| sync_1208 | folP | sync_1208 | sync_1211 | ABC transporter, permease/ATP-binding protein; Identified by match to protein family HMM PF00005; match to protein family HMM PF00664. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.576 |
| sync_1208 | sync_1207 | sync_1208 | sync_1207 | ABC transporter, permease/ATP-binding protein; Identified by match to protein family HMM PF00005; match to protein family HMM PF00664. | Conserved hypothetical protein. | 0.697 |
| sync_1208 | sync_1209 | sync_1208 | sync_1209 | ABC transporter, permease/ATP-binding protein; Identified by match to protein family HMM PF00005; match to protein family HMM PF00664. | S4 domain protein; Identified by match to protein family HMM PF01479. | 0.636 |
| sync_1208 | sync_1212 | sync_1208 | sync_1212 | ABC transporter, permease/ATP-binding protein; Identified by match to protein family HMM PF00005; match to protein family HMM PF00664. | Uncharacterized conserved protein; Identified by match to protein family HMM PF04134. | 0.439 |
| sync_1208 | tpiA | sync_1208 | sync_1210 | ABC transporter, permease/ATP-binding protein; Identified by match to protein family HMM PF00005; match to protein family HMM PF00664. | Triosephosphate isomerase; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. | 0.663 |
| sync_1209 | dnaA | sync_1209 | sync_1933 | S4 domain protein; Identified by match to protein family HMM PF01479. | Chromosomal replication initiator protein DnaA; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids. | 0.434 |
| sync_1209 | folP | sync_1209 | sync_1211 | S4 domain protein; Identified by match to protein family HMM PF01479. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.719 |